典型文献
Wastewater Based Surveillance of SARS-CoV-2:Challenges and Perspective from a Canadian Inter-laboratory Study
文献摘要：
The current rapidly rising 5th wave of the Severe Acute Res-piratory Syndrome Coronavirus 2(SARS-CoV-2),dominated by the omicron variant,has clearly shown the challenges in monitoring,and tracing clinical cases of infection.Omicron has been identified by the World Health Organization(WHO)as a variant of concern(VOC)on November 26th of 2021,be-cause of the reported higher risk of transmission,reinfection,and potential to escape immunity(WHO 2022;Pulliam et al.,2021).As of January 13th,2022,the WHO has reported over 312.8 million total cases of SARS-CoV-2,and over 5.5 million deaths,with cases continuing to rise at an unprecedented rate(WHO,2022).To date,SARS-CoV-2 detection in the com-munity is primarily through clinical testing that involves the gold standard process of nasopharyngeal swab sample collec-tion followed by real time quantitative polymerase chain reac-tion(RT-qPCR)detection.However,omicron's rapid transmis-sion has clearly shown that clinical testing alone cannot meet the needs for monitoring and tracing SARS-CoV-2 infection in communities.With the exponential increase in daily SARS-CoV-2 cases of omicron,many countries are struggling to clini-cally diagnose every infected patient and trace contacts.Public health districts and health care facilities are once again over-whelmed with this wave of the pandemic.Furthermore,many presymptomatic,asymptomatic,and mild cases significantly contribute to the spread and are undetected.Consequently,capacity-constrained clinical testing,as currently exists with omicron wave,systematically underestimates the prevalence of the SARS-CoV-2 pandemic.
文献关键词：
中图分类号：
作者姓名：
Teresa Kumblathan;Nicholas Piroddi;Steve E.Hrudey;Xing-Fang Li
作者机构：
Division of Analytical and Environmental Toxicology,Department of Laboratory Medicine and Pathology,Faculty of Medicine and Dentistry,University of Alberta,Albert T6G 2G3a,Canada
文献出处：
引用格式：
[1]Teresa Kumblathan;Nicholas Piroddi;Steve E.Hrudey;Xing-Fang Li-.Wastewater Based Surveillance of SARS-CoV-2:Challenges and Perspective from a Canadian Inter-laboratory Study)[J].环境科学学报（英文版）,2022(06):229-232
A类：
Pulliam,whelmed,presymptomatic
B类：
Wastewater,Based,Surveillance,SARS,CoV,Challenges,Perspective,from,Canadian,Inter,laboratory,Study,rapidly,rising,5th,wave,Severe,Acute,Res,piratory,Syndrome,Coronavirus,dominated,by,omicron,variant,has,clearly,shown,challenges,monitoring,tracing,clinical,cases,Omicron,been,identified,World,Health,Organization,WHO,concern,VOC,November,26th,cause,reported,higher,risk,transmission,reinfection,potential,escape,immunity,January,13th,over,million,total,deaths,continuing,rise,unprecedented,rate,To,date,detection,primarily,through,testing,that,involves,gold,standard,process,nasopharyngeal,swab,sample,collec,followed,real,quantitative,polymerase,chain,reac,qPCR,However,alone,cannot,meet,needs,communities,With,exponential,increase,daily,many,countries,struggling,diagnose,every,infected,patient,trace,contacts,Public,health,districts,care,facilities,again,this,pandemic,Furthermore,asymptomatic,mild,significantly,contribute,spread,undetected,Consequently,capacity,constrained,currently,exists,systematically,underestimates,prevalence
AB值：
0.588846
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