典型文献
Effects of soy hull polysaccharide on dyslipidemia and pathoglycemia in rats induced by a high-fat-high-sucrose diet
文献摘要：
The present work aimed at investigating the effects of soy hull polysaccharide (SHP) in alleviating adverse effects in rats fed a high-fat-high-sucrose diet. After SHP feeding for 4 weeks, the fasting blood glucose (FBG), serum triglyceride (TG), serum high-density lipoprotein cholesterol (HDL-C), short chain fatty acids (SCFAs), and 16S rDNA gene sequence were determined. Administration of SHP significantly decreased body fat content and TG levels, and increased water intake and HDL-C levels after 4 weeks of treatment. The antihyperglycemic effect of SHP at a dose of 400 mg/kg mb had the most significant effects among the three dosage groups. SHP notably restored the FBG in rats fed a high-fat-high-sucrose diet (P < 0.05). Furthermore, SHP at 400 mg/kg mb increased the abundance of Bacteroidetes and decreased that of Firmicutes and Actinobacteria at the phylum level. The polysaccharide treated groups had significantly higher content of total SCFAs, and the main fermentation products were acetic, propionic, n-valeric and i-valeric acids. Thus, SHP restores blood lipid levels in rats fed a high-fat-high sucrose diet through regulation of the gut microbiota.
文献关键词：
中图分类号：
作者姓名：
Qian Lin;Lina Yang;Lin Han;Ziyi Wang;Mingshuo Luo;Danshi Zhu;He Liu;Xin Li;Yu Feng
作者机构：
College of Food Science and Technology,Bohai University,Jinzhou 121013,China;National&Local Joint Engineering Research Center of Storage,Processing and Safety Control Technology for Fresh Agricultural and Aquatic Products,Jinzhou 121013,China
文献出处：
引用格式：
[1]Qian Lin;Lina Yang;Lin Han;Ziyi Wang;Mingshuo Luo;Danshi Zhu;He Liu;Xin Li;Yu Feng-.Effects of soy hull polysaccharide on dyslipidemia and pathoglycemia in rats induced by a high-fat-high-sucrose diet)[J].食品科学与人类健康（英文）,2022(01):49-57
A类：
pathoglycemia,antihyperglycemic
B类：
Effects,soy,hull,polysaccharide,dyslipidemia,rats,induced,by,sucrose,diet,present,work,aimed,investigating,effects,SHP,alleviating,adverse,fed,After,feeding,weeks,fasting,blood,glucose,FBG,serum,triglyceride,density,lipoprotein,cholesterol,HDL,short,chain,fatty,acids,SCFAs,16S,rDNA,gene,sequence,were,determined,Administration,significantly,decreased,body,content,levels,increased,water,intake,after,treatment,dose,mb,had,most,among,three,dosage,groups,notably,restored,Furthermore,abundance,Bacteroidetes,that,Firmicutes,Actinobacteria,phylum,treated,higher,total,main,fermentation,products,acetic,propionic,valeric,Thus,restores,through,regulation,gut,microbiota
AB值：
0.50385
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