Intestinal microecology is the main component of human microecology. Intestinal mi-croecology consists of intestinal microbiota, intestinal epithelial cells, and intestinal mucosal immune system. These components are interdependent and establish a com-plex interaction network that restricts each other. According to the impact on the human body, there are three categories of symbiotic bacteria, opportunistic patho-gens, and pathogenic bacteria. The intestinal microecology participates in digestion and absorption, and material metabolism, and inhibits the growth of pathogenic mi-croorganisms. It also acts as the body' s natural immune barrier, regulates the innate immunity of the intestine, controls the mucosal barrier function, and also participates in the intestinal epithelial cells' physiological activities such as hyperplasia or apopto-sis. When the steady- state balance of the intestinal microecology is disturbed, the ex-isting core intestinal microbiota network changes and leads to obesity, diabetes, and many other diseases, especially irritable bowel syndrome, inflammatory bowel disease (IBD), and colorectal malignancy. Intestinal diseases, including tumors, are particularly closely related to intestinal microecology. This article systematically discusses the re-search progress on the relationship between IBD and intestinal microecology from the pathogenesis, treatment methods of IBD, and the changes in intestinal microbiota.

Qianhui Fu;Tianyuan Song;Xiaoqin Ma;Jian Cui

School of Pharmacy,Minzu University of China,Beijing,China;Ministry of Education,Key Laboratory of Ethnomedicine,Minzu University of China,Beijing,China

动物模型与实验医学（英文）

[1]Qianhui Fu;Tianyuan Song;Xiaoqin Ma;Jian Cui-.Research progress on the relationship between intestinal microecology and intestinal bowel disease)[J].动物模型与实验医学（英文）,2022(04):297-310

croecology,croorganisms,apopto

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