典型文献
Nanofluidics for single-cell analysis
文献摘要:
Living single-cell analysis is vital for cell biology,disease pathology,drug discovery and medical treat-ment.It is of great significance to reveal the law of creature and to explore the mechanism of serious disease.The conventional single cell analysis focuses on a large number of cells or cell lysis,in order to obtain the average information about cells.Therefore,it fails to analyze the real-time and continu-ous data of differences between the individual cells,thus limiting the development of many fields,such as biomedical.Nanofluidics based biochemical analysis exhibits advantages over conventional methods in terms of small sample volume,rapid turnaround time,straightforward operation,and efficient processing,which has been widely used in complex operations such as single cell capture,separation and single cell detection.Here we review the recent developments of nanofluidic technologies for single-cell analysis,with emphasis on cell trapping,treatment,and biochemical studies.The potential of nanofluidics-based single-cell analysis is discussed.
文献关键词:
中图分类号:
作者姓名:
Zengnan Wu;Ling Lin
作者机构:
Department of Bioengineering,Beijing Technology and Business University,Beijing 100048,China;State Key Laboratory of Chemical Resource Engineering,Beijing University of Chemical Technology,Beijing 100029,China
文献出处:
引用格式:
[1]Zengnan Wu;Ling Lin-.Nanofluidics for single-cell analysis)[J].中国化学快报(英文版),2022(04):1752-1756
A类:
Nanofluidics,nanofluidic,nanofluidics
B类:
single,analysis,Living,vital,biology,disease,pathology,drug,discovery,It,great,significance,reveal,law,creature,explore,mechanism,serious,conventional,focuses,large,number,cells,order,obtain,average,information,about,Therefore,fails,analyze,real,continu,data,differences,between,individual,thus,limiting,many,fields,such,biomedical,biochemical,exhibits,advantages,methods,terms,small,sample,volume,rapid,turnaround,straightforward,efficient,processing,which,been,widely,used,complex,operations,capture,separation,detection,Here,review,recent,developments,technologies,emphasis,trapping,treatment,studies,potential,discussed
AB值:
0.545774
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