典型文献
64Cu radiolabeled nanomaterials for positron emission tomography(PET)imaging
文献摘要：
The prevalence of positron emission tomography(PET)imaging has advanced biomedical applications for its ultrahigh sensitivity,deep tissue penetration and quantitative visualization of diseases in vivo.64Cu with ideal half-life and decay characteristics has been designed as radioactive probes for disease diag-nosis.The currently reported 64Cu-labeled nanomaterials have the advantages of long circulation time in serum,good biocompatibility and mature preparation methods,and have been used in vivo PET imaging,biodistribution and pharmacokinetic monitoring,and imaging guided therapy.At the same time,suitable carrier characteristics and radiolabeling strategies are particularly important in the 64Cu PET imaging pro-cess.In this review,we summarize different imaging probe designs and 64Cu radiolabeling strategies,as well as their eventual applications in biomedicine.The potential challenges and prospects of 64Cu labeled nanomaterials are also described,which provides broad prospects for radiolabeling strategies and further applications.
文献关键词：
中图分类号：
作者姓名：
Xueqian Chen;Wenchao Niu;Zhongying Du;Yong Zhang;Dongdong Su;Xueyun Gao
作者机构：
Department of Chemistry and Biology,Faculty of Environment and Life,Beijing University of Technology,Beijing 100124,China
文献出处：
引用格式：
[1]Xueqian Chen;Wenchao Niu;Zhongying Du;Yong Zhang;Dongdong Su;Xueyun Gao-.64Cu radiolabeled nanomaterials for positron emission tomography(PET)imaging)[J].中国化学快报（英文版）,2022(07):3349-3360
A类：
radiolabeling
B类：
64Cu,radiolabeled,nanomaterials,positron,emission,tomography,PET,imaging,prevalence,has,advanced,biomedical,applications,its,ultrahigh,sensitivity,deep,tissue,penetration,quantitative,visualization,diseases,vivo,ideal,half,life,decay,characteristics,been,designed,radioactive,probes,diag,nosis,currently,reported,have,advantages,long,circulation,serum,good,biocompatibility,mature,preparation,methods,used,biodistribution,pharmacokinetic,monitoring,guided,therapy,At,same,suitable,carrier,strategies,are,particularly,important,cess,In,this,review,summarize,different,designs,well,their,eventual,biomedicine,potential,challenges,prospects,also,described,which,provides,broad,further
AB值：
0.581269
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