典型文献
Impact of rotavirus vaccine implementation on Israeli children:a comparison between pre-and post-vaccination era
文献摘要：
Background Worldwide rotavirus vaccination has resulted in a substantial decrease in rotavirus-induced severe gastroenteritis and related hospitalizations among children.Still,the characterization of patients warranting hospitalization needs to be further elucidated.The purpose of the study is to compare the clinical and laboratory features of children hospitalized with acute rotavirus infection before and after the introduction of routine vaccination.Methods This is a retrospective observational study.Participants were pediatric patients who presented to the Bnai Zion Med-ical Center pediatric emergency department and were diagnosed with rotavirus acute gastroenteritis between 2017 and 2019.Results During the pre-vaccination period(2007-2009),114 infants and young children(median age:14 months,range:1-72 months;59 male,55 female)were hospitalized for rotavirus-induced acute gastroenteritis with a rate of 11.71 positive rotavirus tests per 1000 emergency room visits.In the post-vaccination period(2012-2019),168 infants and young children(median age:17 months,range:0-84 months;90 male,78 female)were hospitalized with a rate of 4.18 positive rotavirus tests per 1000 emergency room visits.There were no statistical differences between the two groups in gender,breast-feeding rates and sibling(s).The proportion of cases with moderate-to-severe dehydration was higher in the post-vaccination children than in the pre-vaccination children.Conclusions Rates of rotavirus-attributed acute gastroenteritis hospitalizations declined from the pre-to the post-vaccination period.Higher rates of dehydration were found in the post-vaccination children.Ongoing surveillance is warranted to better understand the implications of the vaccine.
文献关键词：
中图分类号：
作者姓名：
Hussein Zaitoon;Shaden Hanna;Ellen Bamberger
作者机构：
Department of Pediatrics,Bnai Zion Medical Center,The Ruth and Bruce Rappaport Faculty of Medicine,Technion-Israel Institute of Technology,47 Golomb St.,31048 Haifa,Israel;The Ruth and Bruce Rappaport Faculty of Medicine,Technion-Israel Institute of Technology,Haifa,Israel
文献出处：
引用格式：
[1]Hussein Zaitoon;Shaden Hanna;Ellen Bamberger-.Impact of rotavirus vaccine implementation on Israeli children:a comparison between pre-and post-vaccination era)[J].世界儿科杂志（英文版）,2022(06):417-425
A类：
Israeli,Bnai,Zion
B类：
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AB值：
0.458824
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