典型文献
Two approaches for newborns with critical congenital heart disease:a comparative study
文献摘要:
Background Prenatal diagnosis and planned peripartum care is an unexplored concept in China.This study aimed to evalu-ate the effects of the "prenatal diagnosis and postnatal treatment integrated model" for newborns with critical congenital heart disease.Methods The medical records of neonates (≤ 28 days) admitted to Fuwai Hospital were reviewed retrospectively from Janu-ary 2019 to December 2020.The patients were divided into "prenatal diagnosis and postnatal treatment integrated group"(n =47) and "non-integrated group" (n =69).Results The age of admission to the hospital and the age at surgery were earlier in the integrated group than in the non-integrated group (5.2 ± 7.2 days vs.11.8 ± 8.0 days,P < 0.001;11.9 ± 7.0 days vs.16.5 ± 7.7 days,P =0.001,respectively).The weight at surgery also was lower in the integrated group than in the non-integrated group (3.3 ± 0.4 kg vs.3.6± 0.6 kg,P =0.010).Longer postoperative recovery time was needed in the integrated group,with a median mechanical ventilation time of 97 h (interquartile range 51-259 h) vs.69 h (29-168 h) (P=0.030) and with intensive care unit time of 13.0 days(8.0-21.0 days) vs.9.0 days (4.5-16.0 days) (P=0.048).No significant difference was observed in the all-cause mortality(2.1 vs.8.7%,P =0.238),but it was significantly lower in the integrated group for transposition of the great arteries (0 vs.18.8%,log rank P=0.032).Conclusions The prenatal diagnosis and postnatal treatment integrated model could significantly shorten the diagnosis and hospitalization interval of newborns,and surgical intervention could be performed with a lower risk of death,especially for transposition of the great arteries.
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作者姓名:
Guan-Xi Wang;Kai Ma;Kun-Jing Pang;Xu Wang;Lei Qi;Yang Yang;Feng-Qun Mao;Shou-Jun Li
作者机构:
Pediatric Cardiac Surgery Center,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,No.167 Beilishi Street,Xicheng District,Beijing 100037,China;Department of Echocardiography,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,No.167 Beilishi Street,Xicheng District,Beijing 100037,China
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引用格式:
[1]Guan-Xi Wang;Kai Ma;Kun-Jing Pang;Xu Wang;Lei Qi;Yang Yang;Feng-Qun Mao;Shou-Jun Li-.Two approaches for newborns with critical congenital heart disease:a comparative study)[J].世界儿科杂志(英文版),2022(01):59-66
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0.496519
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