典型文献
Associations of body mass index and hospital-acquired disability with post-discharge mortality in older patients with acute heart failure
文献摘要：
OBJECTIVES To investigate the effect of hospital-acquired disability (HAD) on all-cause mortality after discharge according to the body mass index (BMI) in older patients with acute decompensated heart failure. METHODS We included 408 patients aged ≥ 65 years who were hospitalized for acute decompensated heart failure and had undergone an acute phase of cardiac rehabilitation at the Sakakibara Heart Institute between April 2013 and September 2015 (me-dian age: 82 years, interquartile range (IQR): 76–86; 52％ male). Patients were divided into three groups based on BMI at hospital admission: underweight (< 18.5 kg/m2), normal weight (18.5 to 25 kg/m2), and overweight (≥ 25 kg/m2). HAD was defined as a decrease of at least five points at discharge compared to before hospitalization according to the Barthel Index. RESULTS The median follow-up period was 475 (IQR: 292–730) days, and all-cause mortality during the follow-up period was 84 deaths (21％). According to multivariate Cox regression analysis, being underweight (HR: 1.941, 95％ CI: 1.134?3.321, P = 0.016) or overweight (HR: 0.371, 95％ CI: 0.171?0.803, P = 0.012), with normal BMI as the reference, and HAD (HR: 1.857, 95％ CI:1.062?3.250, P = 0.030) were independently associated with all-cause mortality. Patients with HAD exhibited a significantly lower cumulative survival rate in the underweight group (P = 0.001) and tended to have a lower cumulative survival rate in the normal weight group (P = 0.072). HAD was not significantly associated with cumulative survival in the overweight group (P = 0.392). CONCLUSIONS BMI and HAD independently predicted all-cause mortality after discharge in older patients with acute de-compensated heart failure. Furthermore, HAD was significantly associated with higher all-cause mortality after discharge, espe-cially in the underweight group.
文献关键词：
中图分类号：
作者姓名：
Akihiro Sakuyama;Masakazu Saitoh;Kentaro Hori;Yuichi Adachi;Keigo Iwai;Masatoshi Nagayama
作者机构：
Department of Physical Therapy,Faculty of Health Science,Juntendo University,Tokyo,Japan;Department of Rehabilitation,Sakakibara Heart Institute,Tokyo,Japan;Department of Cardiology,Sakakibara Heart Institute,Tokyo,Japan
文献出处：
引用格式：
[1]Akihiro Sakuyama;Masakazu Saitoh;Kentaro Hori;Yuichi Adachi;Keigo Iwai;Masatoshi Nagayama-.Associations of body mass index and hospital-acquired disability with post-discharge mortality in older patients with acute heart failure)[J].老年心脏病学杂志（英文版）,2022(03):209-217
A类：
OBJECTIVES,Sakakibara
B类：
Associations,body,mass,acquired,disability,post,discharge,mortality,older,patients,acute,heart,failure,To,investigate,effect,HAD,cause,after,according,decompensated,METHODS,We,included,aged,years,who,were,hospitalized,had,undergone,phase,cardiac,rehabilitation,Heart,Institute,between,April,September,interquartile,range,IQR,male,Patients,divided,into,three,groups,admission,underweight,normal,overweight,was,defined,decrease,least,five,points,compared,before,hospitalization,Barthel,Index,RESULTS,median,follow,period,days,during,deaths,According,multivariate,Cox,regression,analysis,being,reference,independently,associated,exhibited,significantly,lower,cumulative,survival,rate,tended,have,not,CONCLUSIONS,predicted,Furthermore,higher,espe,cially
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0.419112
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