Rui HUANG;Pan LIU;Yiguang BAI;Jieqiong HUANG;Rui PAN;Huihua LI;Yeping SU;Quan ZHOU;Ruixin MA;Shaohui ZONG;Gaofeng ZENG-College of Public Hygiene of Guangxi Medical University,Nanning 530021,China;Department of Spine Osteopathic,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China;Department of Orthopaedics,the Third Affiliated Hospital of Xinxiang Medical University,Xinxiang 453000,China;Department of Orthopaedics,Nanchong Central Hospital,the Second Clinical Institute of North Sichuan Medical College,Nanchong 637000,China;Department of Wound Repair,the First People's Hospital of Nanning,Nanning 530022,China

Dan?Dan Zhou;Wei?Qi Bai;Xiao?Tian Zhai;Li?Ping Sun;Yong?Su Zhen;Zhuo?Rong Li;Qing?Fang Miao-NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College,No.1 Tiantan Xili, Beijing 100050, China;Department of Organic Chemistry, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Tiantan Xili,Beijing 100050, China

Yali Chen;Cuihong Yang;Ning Li;Zixing Wang;Peng Wu;Jin Du;Jingmei Jiang-Department of Epidemiology and Biostatistics,Institute of Basic Medical Sciences,Chinese Academy of Medical Science/School of Basic Medicine,Peking Union Medical College,Beijing 100005,China

Hongkun Yang;Yun Xiao;Peng He;Dailong Ai;Qiaosheng Zou;Jian Hu;Qiong Liu;Xiulan Huang;Ting Zheng;Gaoqiong Fan-Crop Ecophysiology and Cultivation Key Laboratory of Sichuan Province,Sichuan Agricultural University,Chengdu 611130,Sichuan,China;Key Laboratory of Crop Eco-Physiology&Farming System in Southwest China,Ministry of Agriculture and Rural Affairs,Chengdu 611130,Sichuan,China;State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China,Ministry of Science and Technology,Chengdu 611130,Sichuan,China

Lei Li;Muhammad Adeel Hassan;Shurong Yang;Furong Jing;Mengjiao Yang;Awais Rasheed;Jiankang Wang;Xianchun Xia;Zhonghu He;Yonggui Xiao-Institute of Crop Sciences,National Wheat Improvement Centre,Chinese Academy of Agricultural Sciences(CAAS),Beijing 100081,China;Electronic Information School,Foshan Polytechnic,Foshan 528137,Guangdong,China;International Maize and Wheat Improvement Centre(CIMMYT)China Office,c/o CAAS,Beijing 100081,China;Department of Plant Sciences,Quaid-i-Azam University,Islamabad 44000,Pakistan

Peng Deng;Insoon Chang;Jiongke Wang;Amr A.Badreldin;Xiyao Li;Bo Yu;Cun-Yu Wang-Laboratory of Molecular Signaling,Division of Oral and Systemic Health Sciences,School of Dentistry,UCLA,Los Angeles,CA,USA;Jonsson Comprehensive Cancer Center,UCLA,Los Angeles,CA,USA;Section of Endodontics,Division of Regenerative and Reconstructive Sciences,School of Dentistry,UCLA,Los Angeles,CA,USA;Division of Preventive and Restorative Sciences,School of Dentistry,UCLA,Los Angeles,CA,USA;Department of Bioengineering,Henry Samueli School of Engineering and Applied Science,UCLA,Los Angeles,CA,USA

Chenchen Zhou;Mengmeng Duan;Daimo Guo;Xinmei Du;Demao Zhang;Jing Xie-State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases,West China Hospital of Stomatology,Sichuan University,Chengdu,China;Department of Cariology and Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,China

Xi Wei;Maobin Yang;Lin Yue;Dingming Huang;Xuedong Zhou;Xiaoyan Wang;Qi Zhang;Lihong Qiu;Zhengwei Huang;Hanguo Wang;Liuyan Meng;Hong Li;Wenxia Chen;Xiaoying Zou;Junqi Ling-Department of Operative Dentistry and Endodontics,Hospital of Stomatology,Guanghua School of Stomatology,Sun Yat-Sen University&Guangdong Provincial Key Laboratory of Stomatology,Guangzhou,Guangdong,China;Department of Endodontology,Maurice H Kornberg School of Dentistry,Temple University,Philadelphia,Pennsylvania,USA;Department of Cariology and Endodontology,Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental Materials,Beijing,China;State Key Laboratory of Oral Diseases&Department of Operative Dentistry and Endodontics,West China Hospital of Stomatology,National Center of Stomatology,National Clinical Research Centre for Oral Diseases,Sichuan University,Chengdu,China;Department of Endodontics,Stomatological Hospital and Dental School of Tongji University,Shanghai Engineering Research Center of Tooth Restoration and Regeneration,Shanghai,China;Department of Endodontics,School of Stomatology,China Medical University,Shenyang,Liaoning,China;Department of Endodontics,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,College of Stomatology,Shanghai Jiao Tong University,National Clinical Research Center for Oral Diseases,National Center for Stomatology,Shanghai Key Laboratory of Stomatology,Shanghai,China;Department of Operative Dentistry&Endodontics,School of Stomatology,The Fourth Military Medical University,Xi'an,China;The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST)&Key Laboratory of Oral Biomedicine Ministry of Education,School and Hospital of Stomatology,Wuhan University,Wuhan,China;Department of Endodontics,Beijing Stomatological Hospital,School of Stomatology,Capital Medical University,Beijing,China;College of Stomatology,Hospital of Stomatology,Guangxi Medical University,Nanning,Guangxi,China

Lixing Zhang;Xintao Yan;Li An;Meijia Wang;Xi Xu;Zhonglin Ma;Mengting Nie;Fangzhou Du;Jingzhong Zhang;Shuang Yu-Suzhou Institute of Biomedical Engineering and Technology,Chinese Academy of Sciences,Suzhou 215163,China;Zhengzhou Institute of Engineering and Technology Affiliated with SIBET,Zhengzhou 450001,China;Academy for Engineering and Technology,Fudan University,Shanghai 200433,China;Xuzhou Medical University,Xuzhou 221004,China

Maryam Tamaddon;Gordon Blunn;Rongwei Tan;Pan Yang;Xiaodan Sun;Shen-Mao Chen;Jiajun Luo;Ziyu Liu;Ling Wang;Dichen Li;Ricardo Donate;Mario Monzón;Chaozong Liu-Institute of Orthopaedic and Musculoskeletal Science,Royal National Orthopaedic Hospital,University College London,Stanmore HA7 4LP,UK;School of Pharmacy and Biomedical Sciences,University of Portsmouth,Portsmouth PO1 2DT,UK;Guangdong Engineering Research Center of Implantable Medical Polymer,Shenzhen Lando Biomaterials Co.,Ltd.,Shenzhen 518107,China;School of Materials Science and Engineering,Tsinghua University,Beijing 100084,China;State Key Laboratory for Manufacturing System Engineering,School of Mechanical Engineering,Xi'an Jiaotong University,Xi'an 710054,China;Departamento de Ingeniería Mecánica,Grupo de Investigación en Fabricación Integrada y Avanzada,Universidad de Las Palmas de Gran Canaria,Campus Universitario de Tafira s/n,35017 Las Palmas,Spain

Rong Li;Songzuo Yu;Xiao Liang;Yu Li;Keng Po Lai-Laboratory of Environmental Pollution and Integrative Omics,Guangxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation,Guilin Medical University,Guilin 541004,China;Department of Neurosurgery,Guigang City People's Hospital,The Eighth Affiliated Hospital of Guangxi Medical University,Guigang 537100,China

Wei Qian;Manfei Zhang;Kaiwen Wan;Yunxia Xie;Siyuan Du;Jiarui Li;Xiongzheng Mu;Jiange Qiu;Xiangyang Xue;Xiahai Zhuang;Yingzhi Wu;Fan Liu;Sijia Wang-State Key Laboratory of Genetic Engineering,Human Phenome Institute,Zhangjiang Fudan International Innovation Center,Fudan University,Shanghai 201203,China;School of Computer Science,Fudan University,Shanghai 200438,China;CAS Key Laboratory of Computational Biology,Shanghai Institute of Nutrition and Health,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai 200031,China;School of Data Science,Fudan University,Shanghai 200433,China;Academy of Medical Science,Zhengzhou University,Zhengzhou,Henan 450052,China;Department of Plastic Surgery,Huashan Hospital,Fudan University,Shanghai 200040,China;CAS Key Laboratory of Genomic and Precision Medicine,Beijing Institute of Genomics,University of Chinese Academy of Sciences,Beijing 100101,China;School of Future Technology,University of Chinese Academy of Sciences,Beijing 101408,China;Center for Excellence in Animal Evolution and Genetics,Chinese Academy of Sciences,Kunming,Yunnan 650223,China

Jinglin Guo;Juan Peng;Jing Han;Ke Wang;Ruijuan Si;Hui Shan;Xiaoying Wang;Ju Zhang-School of Nursing,Qingdao University,Qingdao 266071,China;Surgery of Traditional Chinese Medicine,Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300150,China;School of Pharmacy,Qingdao University,Qingdao 266071,China

Shufang Cai;Bin Hu;Qi Zhu;Tianqi Duo;Xiaoyu Wang;Xian Tong;Xiaorong Luo;Renqiang Yuan;Yaosheng Chen;Jing Wang;Chenglong Luo;Baosong Xing;Delin Mo-State Key Laboratory of Livestock and Poultry Breeding,Guangdong Public Laboratory of Animal Breeding and Nutrition,Guangdong Key Laboratory of Animal Breeding and Nutrition,Institute of Animal Science,Guangdong Academy of Agricultural Sciences,Guangzhou 510640,China,China;State Key Laboratory of Biocontrol,School of Life Sciences,Sun Yat-Sen University,Guangzhou 510006,China;Henan Key Laboratory of Farm Animal Breeding and Nutritional Regulation,Institute of Animal Husbandry and Veterinary Science,Henan Academy of Agricultural Sciences,Zhengzhou 450002,China

DUAN Fei-Peng;LI Yi-Sheng;HU Tian-Yong;PAN Xin-Quan;MA Fang;FENG Yue;QIU Shu-Qi;ZHENG Yi-Qing-Institute of Otolaryngology,Institute of Hearing and Speech of Sun Yat-sen University,Sun Yat-sen Me-morial Hospital,Sun Yat-sen University,Guangzhou 510520,China;Department of Otolaryngology,Longgang E.N.T hospital&Shenzhen Key Laboratory of E.N.T,Institute of E.N.T,Shenzhen 518172,China

YANG Qin-Qin;FANG Ming-Sun;TU Jue;MA Quan-Xin;SHEN Li-Ye;XU Yan-Yun;CHEN Jie;CHEN Min-Li-Academy of Chinese Medicine&Institute of Comparative Medicine,Zhejiang Chinese Medical University,Hangzhou 310053,China;Department of Experimental Animals,Zhejiang Academy of Traditional Chinese Medicine,Hangzhou 310007,China;Department of Vasculocardiology,the First Affiliated Hospital of Zhejiang Chinese Medicine University,Hangzhou 310006,China

Feng-ling Ning;Jie Tao;Dan-dan Li;Lu-lu Tian;Meng-ling Wang;Svetlana Reilly;Cheng Liu;Hui Cai;Hong Xin;Xue-mei Zhang-Minhang Hospital&Department of Pharmacology,School of Pharmacy,Fudan University,Shanghai 201203,China;Department of Central Laboratory and Neurosurgery,Putuo Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200062,China;Division of Cardiovascular Medicine,Radcliffe Department of Medicine,University of Oxford,John Radcliffe Hospital,Oxford,UK;Department of Medicine,Renal Division,Emory University School of Medicine,Atlanta,GA,USA;Shanghai Zhangjiang Institute of Medical Innovation,Shanghai 201204,China

Chao Fang;Jia-wei Guo;Ya-jun Wang;Xiao-qun Li;Hao Zhang;Jin Cui;Yan Hu;Ying-ying Jing;Xiao Chen;Jia-can Su-Department of Orthopedics Trauma,Shanghai Changhai Hospital,Naval Medical University,Shanghai 200433,China;Institute of Translational Medicine,Shanghai University,Shanghai 201901,China;Department of Chemistry,Fudan University,Shanghai 200433,China;Shanghai Clinical Research Center for Aging and Medicine,Shanghai 200040,China

Liu-shan Chen;Meng Zhang;Peng Chen;Xiao-feng Xiong;Pei-qing Liu;Hai-bin Wang;Jun-jian Wang;Juan Shen-Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances,Guangdong Pharmaceutical University,Guangzhou 510006,China;Department of Orthopedics,Henan Provincial People's Hospital,People's Hospital of Zhengzhou University,People's Hospital of Henan University,Zhengzhou 450003,China;The First Clinical Medical College,Guangzhou University of Chinese Medicine,Guangzhou 510405,China;Department of Laboratory of New Drug Design and Evaluation,School of Pharmaceutical Sciences,Sun Yat-Sen University,Guangzhou 510006,China

Xiao-qin Liu;Yu-fei Zhang;Hong-yan Ding;Ming-ming Yan;Zheng Jiao;Ming-kang Zhong;Chun-lai Ma-Department of Pharmacy,Huashan Hospital,Fudan University,Shanghai 200040,China;Department of Neurology,Huashan Hospital,Fudan University,Shanghai 200040,China;Department of Pharmacy,Shanghai Chest Hospital,Shanghai Jiao Tong University,Shanghai 200030,China