典型文献
Microenvironmental stiffness mediates cytoskeleton re-organization in chondrocytes through laminin-FAK mechanotransduction
文献摘要：
INTRODUCTION
It is well recognized that microenvironmental mechanics mediate cell behaviors, control cell differentiation, and determine cell fate1–2. The stiffness of extracellular matrix (ECM) is one of the key microenvironmental biomechanical factors, which plays an indis-pensable role in organ development3, tissue maturation4 and disease occurrence5. Recent research progress has begun to reveal the important regulatory role of microenvironmental stiffness on cell behaviors based on different kinds of cell types. For stem cells, microenvironmental stiffness could direct the multiple differentia-tions toward osteogenesis, chondrogenesis, adipogenesis and neurogenesis of bone marrow stem cells (BMSCs)2,6, adipose-derived stromal cells (ASCs)7, and odontogenic stem cells8–9.
文献关键词：
中图分类号：
作者姓名：
Chenchen Zhou;Mengmeng Duan;Daimo Guo;Xinmei Du;Demao Zhang;Jing Xie
作者机构：
State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases,West China Hospital of Stomatology,Sichuan University,Chengdu,China;Department of Cariology and Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,China
文献出处：
引用格式：
[1]Chenchen Zhou;Mengmeng Duan;Daimo Guo;Xinmei Du;Demao Zhang;Jing Xie-.Microenvironmental stiffness mediates cytoskeleton re-organization in chondrocytes through laminin-FAK mechanotransduction)[J].国际口腔科学杂志（英文版）,2022(02):182-191
A类：
Microenvironmental,fate1,development3,maturation4,occurrence5,chondrogenesis,cells8
B类：
stiffness,mediates,cytoskeleton,organization,chondrocytes,through,laminin,FAK,mechanotransduction,INTRODUCTION,
It,well,recognized,that,microenvironmental,mechanics,behaviors,control,differentiation,determine,extracellular,matrix,ECM,key,biomechanical,factors,which,plays,indis,pensable,role,tissue,disease,Recent,research,progress,has,begun,reveal,important,regulatory,kinds,types,For,stem,could,direct,multiple,tions,toward,osteogenesis,adipogenesis,neurogenesis,bone,marrow,BMSCs,adipose,derived,stromal,ASCs,odontogenic
AB值：
0.583283
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
