典型文献
Iron, the endolysosomal system and neuroinflammation: a matter of balance
文献摘要：
Iron accumulation and neuroinflammation are cardinal features of many neurodegenerative diseases (Urrutia et al., 2021). However, the hierarchy in the pathogenic mechanisms and the molecular connections between these processes are still obscure. In this perspective, we will discuss current evidence showing that aging, the main risk factor for neurodegenerative diseases, negatively impacts lysosomal function by triggering a paradoxical condition of iron accumulation accompanied by functional iron deficiency. This condition is self-sustaining in the neuroinflammatory process.
文献关键词：
中图分类号：
作者姓名：
Daniel A.Bórquez
作者机构：
Center for Biomedical Research,Faculty ofMedicine,Universidad Diego Portales,Santiago,Chile;Department of Biology,Faculty of Sciences,Universidad de Chile,Santiago,Chile
文献出处：
引用格式：
[1]Daniel A.Bórquez-.Iron, the endolysosomal system and neuroinflammation: a matter of balance)[J].中国神经再生研究（英文版）,2022(05):1003-1004
A类：
endolysosomal,Urrutia
B类：
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AB值：
0.648242
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
