典型文献
Estrogens still represent an attractive therapeutic approach for Alzheimer 's disease
文献摘要：
Alzheimer's disease (AD) is a progressive neurodegenerative condition that goes from mild cognitive impairment in prodromal disease to severely disabling deficits in advanced stages. The risk for AD development, as well as progression and severity, clearly differ between men and women (Pike, 2017). Epidemiological studies have shown that there is a significantly increased prevalence in the development of AD in women compared to men, which is usually explained by the longer lifespan of women. This increased frequency may be due to the interplay between age and sex, in which genetic factors together with hormonal and metabolic patterns play a crucial role. Moreover, cognitive impairment has been confirmed to be greater in women than in men at the same stage of AD, likely due to reduced estrogen levels in post-menopausal women (Laws et al., 2016).
文献关键词：
中图分类号：
作者姓名：
Elena Tamagno
作者机构：
Department of Neuroscience,University of Torino,Torino,Italy;Neuroscience Institute of Cavalieri Ottolenghi Foundation(NICO),University of Torino,Torino,Italy
文献出处：
引用格式：
[1]Elena Tamagno-.Estrogens still represent an attractive therapeutic approach for Alzheimer 's disease)[J].中国神经再生研究（英文版）,2022(01):93-94
A类：
Estrogens,prodromal,Pike
B类：
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AB值：
0.594921
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