典型文献
Primary biliary cholangitis:personalized medicine for optimal therapeutic opportunities
文献摘要：
Primary biliary cholangitis(PBC)is a chronic cholestatic liver disease that is characterized by inflammation of the interlobular bile ducts.Although PBC is a slowly progressive disease,with a nat-ural history of 10-15 years leading to end-stage liver disease,high-risk cases may rapidly progress to decompensated cirrhosis or even death.As the most common autoimmune liver disease,the preva-lence of PBC has been increasing globally,largely due to increased disease awareness,improved diagnosis,and treatment with ursodeoxycholic acid(UDCA).PBC is more likely to occur in mid-dle-aged women,with a female-to-male ratio ranging from 1.6 to 10;however,men have a higher disease severity[1,2].
文献关键词：
中图分类号：
作者姓名：
Yulong Shang;Patrick S.C.Leung;M.Eric Gershwin;Ying Han
作者机构：
National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases,Xijing Hospital,Air Force Military Medical University,Xi'an 710032,China;Division of Rheumatology,Allergy and Clinical Immunology,University of California,Davis 95616,USA
文献出处：
引用格式：
[1]Yulong Shang;Patrick S.C.Leung;M.Eric Gershwin;Ying Han-.Primary biliary cholangitis:personalized medicine for optimal therapeutic opportunities)[J].科学通报（英文版）,2022(24):2498-2501
A类：
interlobular
B类：
Primary,biliary,cholangitis,personalized,medicine,optimal,therapeutic,opportunities,PBC,chronic,cholestatic,liver,disease,that,characterized,by,inflammation,bile,ducts,Although,slowly,progressive,nat,ural,history,years,leading,end,stage,risk,cases,may,rapidly,decompensated,cirrhosis,even,death,most,common,autoimmune,preva,lence,has,been,increasing,globally,largely,due,increased,awareness,improved,diagnosis,treatment,ursodeoxycholic,acid,UDCA,more,likely,occur,mid,dle,aged,women,female,ratio,ranging,from,however,have,higher,severity
AB值：
0.710587
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
