典型文献
Research advances on how metformin improves memory impairment in "chemobrain"
文献摘要：
Cognitive impairment caused by chemotherapy, referred to as "chemobrain," is observed in approximately 70％ of cancer survivors. However, it is not completely understood how chemotherapy induces cognitive dysfunction, and clinical treatment strategies for this problem are lacking. Metformin, used as a first-line treatment for type 2 diabetes mellitus, is reported to reduce the effects of chemobrain. Recently, several studies have examined the effect of metformin in rescuing chemobrain. This review discusses recent clinical/preclinical studies that addressed some mechanisms of chemobrain and evaluates the effect of metformin in rescuing chemobrain and its potential mechanisms of action.
文献关键词：
中图分类号：
作者姓名：
Ahmad Alhowail
作者机构：
Department of Pharmacology and Toxicology,College of Pharmacy,Qassim University,Buraidah,Kingdom of Saudi Arabia;Department of Medicinal Chemistry and Pharmacognosy,College of Pharmacy,Qassim University,Buraydah,Kingdom of Saudi Arabia
文献出处：
引用格式：
[1]Ahmad Alhowail-.Research advances on how metformin improves memory impairment in "chemobrain")[J].中国神经再生研究（英文版）,2022(01):15-19
A类：
chemobrain
B类：
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AB值：
0.583083
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