典型文献
The composition,function,and regulation of adipose stem and progenitor cells
文献摘要：
White adipose tissue(WAT)is a highly plastic organ that plays a central role in regulating whole-body energy metabolism.Adipose stem and progenitor cells(ASPCs)are essential components of the stromal vascular fraction(SVF)of adipose tissue.They give rise to mature adipocytes and play a critical role in maintaining adipose tissue function.However,the molecular heterogeneity and functional diversity of ASPCs are still poorly understood.Recently,single-cell RNA sequencing(scRNA-seq)analysis has iden-tified distinct subtypes of ASPCs in murine and human adipose tissues,providing new insights into the cellular complexity of ASPCs among multiple fat depots.This review summarizes the current knowledge on ASPC populations,including their markers,functions,and regulatory mechanisms.Targeting one or several of these cell populations may ameliorate metabolic disorders by promoting adaptive hyperplastic adipose growth.
文献关键词：
中图分类号：
作者姓名：
Xiyan Liao;Haiyan Zhou;Tuo Deng
作者机构：
National Clinical Research Center for Metabolic Diseases,and Department of Metabolism and Endocrinology,The Second Xiangya Hospital of Central South University,Changsha,Hunan 410000,China;Key Laboratory of Diabetes Immunology,Ministry of Education,and Metabolic Syndrome Research Center,The Second Xiangya Hospital of Central South University,Changsha,Hunan 410000,China;Department of Endocrinology,Endocrinology Research Center,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China;National Clinical Research Center for Geriatric Disorders,Xiangya Hospital,Changsha,Hunan 410008,China;Clinical Immunology Center,The Second Xiangya Hospital of Central South University,Changsha,Hunan 410000,China
文献出处：
引用格式：
[1]Xiyan Liao;Haiyan Zhou;Tuo Deng-.The composition,function,and regulation of adipose stem and progenitor cells)[J].遗传学报,2022(04):308-315
A类：
ASPCs
B类：
composition,regulation,adipose,stem,progenitor,cells,White,WAT,highly,organ,that,plays,central,role,regulating,whole,body,energy,metabolism,Adipose,are,essential,components,stromal,vascular,fraction,SVF,They,give,rise,mature,adipocytes,critical,maintaining,However,molecular,heterogeneity,functional,diversity,still,poorly,understood,Recently,single,sequencing,scRNA,analysis,has,iden,tified,distinct,subtypes,murine,human,tissues,providing,new,insights,into,cellular,complexity,among,multiple,fat,depots,This,review,summarizes,current,knowledge,populations,including,their,markers,functions,regulatory,mechanisms,Targeting,several,these,may,ameliorate,metabolic,disorders,by,promoting,adaptive,hyperplastic,growth
AB值：
0.67878
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
