典型文献
Versatile subtypes of pericytes and their roles in spinal cord injury repair,bone development and repair
文献摘要：
Vascular regeneration is a challenging topic in tissue repair.As one of the important components of the neurovascular unit(NVU),pericytes play an essential role in the maintenance of the vascular network of the spinal cord.To date,subtypes of pericytes have been identified by various markers,namely the PDGFR-β,Desmin,CD146,and NG2,each of which is involved with spinal cord injury(SCI)repair.In addition,pericytes may act as a stem cell source that is important for bone development and regeneration,whilst specific subtypes of pericyte could facilitate bone fracture and defect repair.One of the major challenges of pericyte biology is to determine the specific markers that would clearly distinguish the different subtypes of pericytes,and to develop efficient approaches to isolate and propagate pericytes.In this review,we discuss the biology and roles of pericytes,their markers for identification,and cell differentiation capacity with a focus on the potential application in the treatment of SCI and bone diseases in orthopedics.
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作者姓名：
Sipin Zhu;Min Chen;Yibo Ying;Qiuji Wu;Zhiyang Huang;Wenfei Ni;Xiangyang Wang;Huazi Xu;Samuel Bennett;Jian Xiao;Jiake Xu
作者机构：
Department of Orthopaedics,The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University,Wenzhou,Zhejiang 325000,China;Molecular Pharmacology Research Centre,School of Pharmaceutical Sciences,Wenzhou Medical University,Wenzhou,Zhejiang 325035,China;Molecular Laboratory,School of Biomedical Sciences,The University of Western Australia,Perth,WA 6009,Australia
文献出处：
引用格式：
[1]Sipin Zhu;Min Chen;Yibo Ying;Qiuji Wu;Zhiyang Huang;Wenfei Ni;Xiangyang Wang;Huazi Xu;Samuel Bennett;Jian Xiao;Jiake Xu-.Versatile subtypes of pericytes and their roles in spinal cord injury repair,bone development and repair)[J].骨研究（英文版）,2022(02):253-264
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0.524136
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