典型文献
Catalytic asymmetric synthesis of chiral azo compounds via interrupted Japp-Klingemann reaction with aryldiazonium salts
文献摘要：
Asymmetric synthesis of enantioenriched azo compounds bearing tetrasubstituted stereocenter was achieved through chiral N,N'-dioxide/metal Lewis acid promoted interrupted Japp-Klingemann reaction of aryldiazonium tetrafluoroborate salts with nu-cleophiles under mild conditions.This protocol features wide substrate scope and good functional group compatibility.Azaarene-containing chiral azo compounds were stable enough in Japp-Klingemann reaction condition.The key to success of the reaction was the employment of metal salt/N,N-dioxide ligand and the dual-task roles of the base.Moreover,the X-ray crystal structure of Ni(Ⅱ)/N,N-dioxide/substrate complex confirmed that the substrate was activated by bidentate coordination,which shed light on the origin of chiral control of the reaction.
文献关键词：
中图分类号：
作者姓名：
Yan Wang;Aying Yihuo;Lifeng Wang;Shunxi Dong;Xiaoming Feng
作者机构：
Key Laboratory of Green Chemistry&Technology,Ministry of Education,College of Chemistry,Sichuan University,Chengdu 610064,China
文献出处：
引用格式：
[1]Yan Wang;Aying Yihuo;Lifeng Wang;Shunxi Dong;Xiaoming Feng-.Catalytic asymmetric synthesis of chiral azo compounds via interrupted Japp-Klingemann reaction with aryldiazonium salts)[J].中国科学:化学（英文版）,2022(03):546-553
A类：
Japp,Klingemann,aryldiazonium,tetrasubstituted,stereocenter,cleophiles,Azaarene
B类：
Catalytic,asymmetric,synthesis,chiral,compounds,via,interrupted,reaction,salts,Asymmetric,enantioenriched,bearing,was,achieved,through,dioxide,metal,Lewis,acid,promoted,tetrafluoroborate,nu,under,mild,conditions,This,protocol,features,wide,substrate,scope,good,functional,group,compatibility,containing,were,stable,enough,key,success,employment,ligand,dual,task,roles,base,Moreover,ray,crystal,structure,complex,confirmed,that,activated,by,bidentate,coordination,which,shed,light,origin,control
AB值：
0.503378
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