典型文献
Mechanistic insight into the synergistic Cu/Pd-catalyzed carbonylation of aryl iodides using alcohols and dioxygen as the carbonyl source
文献摘要：
Pd-catalyzed carbonylation,as an efficient synthetic approach to the installation of carbonyl groups in organic compounds,has been one of the most important research fields in the past decade.Although elegant reactions that allow highly selective carbonylations have been developed,straightforward routes with improved reaction activity and broader substrate scope remain long-term challenges for new practical applications.Here,we show a new type of synergistic Cu/Pd-catalyzed carbonylation reaction using alcohols and dioxgen as the carbonyl sources.A broad range of aryl iodides and alcohols are compatible with this protocol.The reaction is concise and practical due to the ready availability of the starting materials and the scalability of the reaction.In addition,the reaction affords lactones and lactams in an intermolecular fashion.Moreover,DFT calculations have been performed to study the detailed mechanisms.
文献关键词：
中图分类号：
作者姓名：
Junxuan Li;Jinlei Zhou;Yumei Wang;Yue Yu;Qiang Liu;Tilong Yang;Huoji Chen;Hua Cao
作者机构：
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering &Technology Research Center,Guangdong Pharmaceutical University,Zhongshan 528458,China;School of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,China;The Hong Kong University of Science and Technology,Clear Water Bay,Kowloon,Hong Kong,China
文献出处：
引用格式：
[1]Junxuan Li;Jinlei Zhou;Yumei Wang;Yue Yu;Qiang Liu;Tilong Yang;Huoji Chen;Hua Cao-.Mechanistic insight into the synergistic Cu/Pd-catalyzed carbonylation of aryl iodides using alcohols and dioxygen as the carbonyl source)[J].中国科学:化学（英文版）,2022(01):68-74
A类：
carbonylations,dioxgen
B类：
Mechanistic,insight,into,synergistic,Pd,catalyzed,aryl,iodides,using,alcohols,dioxygen,efficient,synthetic,approach,installation,groups,organic,compounds,has,been,most,important,research,fields,past,decade,Although,elegant,reactions,that,allow,highly,selective,have,developed,straightforward,routes,improved,activity,broader,substrate,scope,remain,long,challenges,new,practical,applications,Here,we,show,type,sources,range,are,compatible,this,protocol,concise,due,ready,availability,starting,materials,scalability,In,addition,affords,lactones,lactams,intermolecular,fashion,Moreover,DFT,calculations,performed,study,detailed,mechanisms
AB值：
0.581926
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