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典型文献
Natural lotus root-based scaffolds for bone regeneration
文献摘要:
A high incidence of bone defects and the limitation of autologous bone grafting require 3D scaffolds for bone repair.Compared with synthetic materials,natural edible materials possess outstanding advantages in terms of biocompatibility,bioactivities and low manufacturing cost for bone tissue engineering.In this work,attracted by the natural porous/fabric structure,good biocompatibility and bioactivities of the lotus root,the lotus root-based scaffolds were fabricated and investigated their potential to serve as natural porous bone tissue engineering scaffolds.The results indicated that the lotus root-based scaffolds possess suitable natural microstructure,excellent biocompatibility and promising functions,such as antioxidant capacity and angiogenesis promotion.Remarkably,lotus root scaffolds showed encouraging possibility of bone tissue engineering while the mineralized lotus root could further improve the bone regeneration in vivo.All the results demonstrated the bone regeneration potential of lotus root-based scaffolds equipped with suitable natural architecture,excellent biocompatibility,specific bioactivities and low manufacturing cost.
文献关键词:
作者姓名:
Keqing Huang;Jun Huang;Jinmin Zhao;Zhipeng Gu;Jun Wu
作者机构:
School of Biomedical Engineering,Sun Yat-sen University,Shenzhen 518107,China;Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,China;Guangdong Academy of Sciences,Institute of Biological and Medical Engineering,Guangzhou 510316,China;Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China;Research Institute of Sun Yat-sen University in Shenzhen,Shenzhen 518057,China;College of Polymer Science and Engineering,State Key Laboratory of Polymer Materials Engineering,Sichuan University,Chengdu 610065,China
引用格式:
[1]Keqing Huang;Jun Huang;Jinmin Zhao;Zhipeng Gu;Jun Wu-.Natural lotus root-based scaffolds for bone regeneration)[J].中国化学快报(英文版),2022(04):1941-1945
A类:
B类:
Natural,lotus,root,scaffolds,bone,regeneration,high,incidence,defects,limitation,autologous,grafting,require,repair,Compared,synthetic,materials,natural,edible,possess,outstanding,advantages,terms,biocompatibility,bioactivities,low,manufacturing,cost,tissue,engineering,In,this,work,attracted,by,porous,good,were,fabricated,investigated,their,potential,serve,results,indicated,that,suitable,microstructure,excellent,promising,functions,such,antioxidant,capacity,angiogenesis,promotion,Remarkably,showed,encouraging,possibility,while,mineralized,could,further,improve,vivo,All,demonstrated,equipped,architecture,specific
AB值:
0.485234
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