Attempt of developing bio-safety and functional layered double hydroxides(LDHs)modified plasma elec-trolytic oxidation(PEO)coatings,has become a hotspot in the protection of magnesium(Mg)based biomedical implants.In the present work,Mg-Fe LDH films with different Fe contents were fabricated on PEO coating via a novel two-step method:firstly,the FeOOH films were prepared by immersing PEO sample in Fe2+-containing solution,and then Mg-Fe LDH films were formed by transforming the FeOOH films via a hydrothermal treatment in water.The highly-oriented LDH nano-sheets could enhance the anti-corrosion performance of PEO coating,which was proved by the results of electrochemical test,hy-drogen evolution and corroded morphology.PEO/Mg-Fe LDH coatings showed a low hemolysis rate(less 5％)than PEO coating.In addition,PEO/Mg-Fe LDH coatings were more favorable for cell adhesion and proliferation than PEO coating.Moreover,PEO/Mg-Fe LDH coatings showed good photothermal conver-sion property,which demonstrated the excellent rapid antibacterial effect under NIR light.In vitro cul-ture of rat bone marrow stem cell(rBMSC)suggested that cells cultured in the extract of PEO/Mg-Fe LDH coatings had a better osteogenic activity.In vivo subcutaneous implantation test revealed that PEO/Mg-Fe LDH coatings exhibited good anti-corrosion and histocompatibility.

Dongdong Zhang;Jielong Zhou;Feng Peng;Ji Tan;Xianming Zhang;Shi Qian;Yuqin Qiao;Yu Zhang;Xuanyong Liu

State Key Laboratory of High Performance Ceramics and Superfine Microstructure,Shanghai Institute of Ceramics,Chinese Academy of Sciences,Shanghai 200050,China;Center of Materials Science and Optoelectronics Engineering,University of Chinese Academy of Sciences,Beijing 100049,China;Department of Orthopedics.Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences.Guangzhou,Guangdong 510080,China;Cixi Center of Biomaterials Surface Engineering.Shanghai Institute of Ceramics,Chinese Academy of Sciences,Ningbo 315300,China;School of Chemistry and Materials Science,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,1 Sub-lane Xiangshan,Hangzhou 310024,China

材料科学技术（英文版）

[1]Dongdong Zhang;Jielong Zhou;Feng Peng;Ji Tan;Xianming Zhang;Shi Qian;Yuqin Qiao;Yu Zhang;Xuanyong Liu-.Mg-Fe LDH sealed PEO coating on magnesium for biodegradation control,antibacteria and osteogenesis)[J].材料科学技术（英文版）,2022(10):57-67

antibacteria,Attempt,trolytic

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