典型文献
A modular single-cell pipette microfluidic chip coupling to ETAAS and ICP-MS for single cell analysis
文献摘要：
Accurate single-cell capture is a crucial step for single cell biological and chemical analysis.Conventional single-cell capturing often confront operational complexity,limited efficiency,cell damage,large scale but low accuracy,incompetence in the acquirement of nano-upgraded single-cell liquid.Flow cytometry has been widely used in large-scale single-cell detection,while precise single-cell isolation relies on both a precision operating platform and a microscope,which is not only extremely inefficient,but also not conducive to couple with modern analytical instruments.Herein,we develop a modular single-cell pipette(mSCP)microfluidic chip with high efficiency and strong applicability for accurate direct capture of single viable cell from cell suspensions into nanoliter droplets(30-1000 nL).The mSCP is used as a sampling platform for the detection of CdTe quantum dots in single cells with electrothermal atomic absorption spectrometry(ETAAS)for the first time.It also ensures precise single-cell sampling and detection by inductively coupled plasma mass spectrometry(ICP-MS).
文献关键词：
中图分类号：
作者姓名：
Xing Wei;Meng Yang;Ze Jiang;Jinhui Liu;Xuan Zhang;Mingli Chen;Jianhua Wang
作者机构：
Research Center for Analytical Sciences,Department of Chemistry,College of Sciences,Northeastern University,Shenyang 110819,China
文献出处：
引用格式：
[1]Xing Wei;Meng Yang;Ze Jiang;Jinhui Liu;Xuan Zhang;Mingli Chen;Jianhua Wang-.A modular single-cell pipette microfluidic chip coupling to ETAAS and ICP-MS for single cell analysis)[J].中国化学快报（英文版）,2022(03):1373-1376
A类：
ETAAS,mSCP,nanoliter
B类：
modular,single,pipette,microfluidic,chip,coupling,ICP,analysis,Accurate,capture,crucial,step,biological,chemical,Conventional,capturing,often,confront,operational,complexity,limited,efficiency,damage,large,scale,but,accuracy,incompetence,acquirement,upgraded,liquid,Flow,cytometry,has,been,widely,used,detection,while,precise,isolation,relies,both,precision,operating,platform,microscope,which,not,only,extremely,inefficient,also,conducive,modern,analytical,instruments,Herein,we,develop,high,strong,applicability,accurate,direct,viable,from,suspensions,into,droplets,nL,sampling,CdTe,quantum,dots,cells,electrothermal,atomic,absorption,spectrometry,first,It,ensures,by,inductively,coupled,plasma,mass
AB值：
0.583546
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