首站-论文投稿智能助手
典型文献
Designing DNA cage-based immuno-fluorescence strategy for rapid diagnosis of clinical cervical cancer tissues
文献摘要:
Exploiting a tissue diagnosis method to abstain the involuted operating and consume valuable reagents while realizing high-speed and inexpensive pathological grading technology to supply a better scheme for cancer therapy is a significant method of cancers detection.A promising immuno-fluorescence strat-egy was rationally designed and synthesized by loading ruthenium complex into cervical cancer-targeted DNA-cage,which was well used to realize high-speed and inexpensive diagnosis of clinical cervical cancer tumor tissues avoiding the traditional multi-stage process,thus demonstrating high application potential in clinical pathological grading and surgical judgment.Moreover,it has been finding that Apts-DNA@Ru can enrichment in the tumor region,interestingly,no enrichment in normal cervical cancer tissue.It has the potential to realize the integration of in vivo diagnose and further synchronous treatment in the near future.Thence,this study demonstrates a strategy for integration of cancer-targeted DNA-cage and fluo-rescent RuPOP as alternative IHC reagents for next-generation more rapid convenient cancer detection.
文献关键词:
作者姓名:
Juanjuan Li;Hongjie Luo;Xueqiong Zhu;Jianfu Zhao;Tianfeng Chen
作者机构:
Department of Oncology,The First Affiliated Hospital,and Department of Chemistry,Jinan University,Guangzhou 510632,China;Department of Obstetrics and Gynecology,The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University,Wenzhou 325000,China
引用格式:
[1]Juanjuan Li;Hongjie Luo;Xueqiong Zhu;Jianfu Zhao;Tianfeng Chen-.Designing DNA cage-based immuno-fluorescence strategy for rapid diagnosis of clinical cervical cancer tissues)[J].中国化学快报(英文版),2022(02):788-792
A类:
abstain,involuted,Apts,Thence,RuPOP
B类:
Designing,cage,immuno,fluorescence,strategy,rapid,diagnosis,clinical,cervical,tissues,Exploiting,method,operating,consume,valuable,reagents,while,realizing,high,speed,inexpensive,pathological,grading,technology,supply,better,scheme,therapy,significant,cancers,detection,promising,was,rationally,designed,synthesized,by,loading,ruthenium,complex,into,targeted,which,well,used,realize,tumor,avoiding,traditional,multi,stage,process,thus,demonstrating,application,potential,surgical,judgment,Moreover,has,been,finding,that,enrichment,region,interestingly,normal,It,integration,vivo,diagnose,further,synchronous,treatment,near,future,this,study,demonstrates,rescent,alternative,IHC,next,generation,more,convenient
AB值:
0.538169
相似文献
Decorating rare-earth fluoride upconversion nanoparticles on AuNRs@Ag core-shell structure for NIR light-mediated photothermal therapy and bioimaging
Jingzhi Dou;Bei Chen;Guixia Liu;Xiangting Dong;Wensheng Yu;Jinxian Wang;Yunxiao Zhang;Zhanguo Li;Jiang Zhu-Key Laboratory of Applied Chemistry and Nanotechnology at Universities of Jilin Province,Changchun University of Science and Technology,Changchun 130022,China;Key Laboratory of Artificial Micro-and Nano-Structures of Ministry of Education,School of Physics and Technology,Wuhan University,Wuhan 430072,China;Tianjin Jinhang Technical Physics Institute,Tianjin 300070,China;School of Optoelectronic Engineering,Changchun University of Science and Technology,Changchun 130022,China;School of Foreign Languages,Changchun University of Science and Technology,Changchun 130022,China
A facile phototheranostic nanoplatform integrating NIR-Ⅱ fluorescence/PA bimodal imaging and image-guided surgery/PTT combinational therapy for improved antitumor efficacy
Xiuping Han;Wenyou Fang;Tianqi Zhang;Xuan Zhong;Kun Qian;Zhitao Jiang;Rongfeng Hu;Guoqiang Shao;Lei Zhang;Qing Zhang-Department of Pharmaceutics and Key Laboratory of Cardiovascular&Cerebrovascular Medicine,School of Pharmacy,Nanjing Medical University,Nanjing 211166,China;Department of Nuclear Medicine,Nanjing First Hospital,Nanjing Medical University,Nanjing 211166,China;Anhui Province Key Laboratory of Pharmaceutical Preparation Technology and Application,Anhui Province Engineering Technology Research Center of Modern Pharmaceutical Preparation,Anhui University of Chinese Medicine,Hefei 230012,China;Department of Nuclear Medicine,Taizhou People's Hospital,Nanjing University of Chinese Medicine,Taizhou 225300,China;Center for Molecular Imaging Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;State Key Laboratory of Organic Electronics and Information Displays&Institute of Advanced Materials(IAM),Nanjing University of Posts&Telecommunications,Nanjing 210023,China
Genetically encoded BRET-activated photodynamic therapy for the treatment of deep-seated tumors
Elena I.Shramova;Stepan P.Chumakov;Victoria O.Shipunova;Anastasiya V.Ryabova;Georgij B.Telegin;Andrei V.Kabashin;Sergey M.Deyev;Galina M.Proshkina-Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry,Russian Academy of Sciences,16/10 Miklukho-Maklaya Street,Moscow 117997,Russia;MEPhI(Moscow Engineering Physics Institute),Institute of Engineering Physics for Biomedicine(PhysBio),31 Kashirskoe shosse,Moscow 115409,Russia;Prokhorov General Physics Institute,Russian Academy of Sciences,Vavilova,38,Moscow 119991,Russia;Branch of Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry,Russian Academy of Sciences,Prospect Nauki 6,Pushchino 142290,Russia;Aix Marseille University,CNRS,LP3,163 Ave.De Luminy,Case 917,13288 Marseille,France
A metabolic acidity-activatable calcium phosphate probe with fluorescence signal amplification capabilities for non-invasive imaging of tumor malignancy
Qian Jia;Ruili Zhang;Yongdong Wang;Haohao Yan;Zheng Li;Yanbin Feng;Yu Ji;ZUO Yang;Yang Yang;Kanyi Pu;Zhongliang Wang-Laboratory of Molecular Imaging and Translational Medicine (MITM),Engineering Research Center of Molecular & Neuroimaging,Ministry of Education,School of Life Science and Technology,Xidian University,Xi'an 710126,China;Department of Thoracic Surgery,Shanghai Pulmonary Hospital,School of Medicine,Tongji University,Shanghai 200433,China;School of Materials Science and Engineering,Tongji University,Shanghai 201804,China;School of Chemical and Biomedical Engineering,Nanyang Technological University,Singapore 637457,Singapore;Academy of Advanced Interdisciplinary Research,Xidian University,Xi'an 710071,China
Abrogation of HnRNP L enhances anti-PD-1 therapy efficacy via diminishing PD-L1 and promoting CD8+T cell-mediated ferroptosis in castration-resistant prostate cancer
Xumin Zhou;Libin Zou;Hangyu Liao;Junqi Luo;Taowei Yang;Jun Wu;Wenbin Chen;Kaihui Wu;Shengren Cen;Daojun Lv;Fangpeng Shu;Yu Yang;Chun Li;Bingkun Li;Xiangming Mao-Department of Urology,Zhujiang Hospital,Southern Medical University,Guangzhou 510280,China;Second Department of Hepatobiliary Surgery,Zhujiang Hospital,Southern Medical University,Guangzhou 510280,China;Department of Urology,Minimally Invasive Surgery Center,the First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510120,China;Department of Urology,Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou 510623,China;Department of Urology,Peking University Shenzhen Hospital,Shenzhen 518036,China;Nursing Department,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China
Cooperative coordination-mediated multi-component self-assembly of"all-in-one"nanospike theranostic nano-platform for MRI-guided synergistic therapy against breast cancer
Xiaojie Chen;Xudong Fan;Yue Zhang;Yinghui Wei;Hangsheng Zheng;Dandan Bao;Hengwu Xu;Ji-Gang Piao;Fanzhu Li;Hongyue Zheng-School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,China;Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,China;Department of Dermatology&Cosmetology,The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Traditional Chinese Medicine),Hangzhou 310006,China;Department of Pharmacy,Jinhua People's Hospital,Jinhua 321000,China;Academy of Chinese Medical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,China;Libraries of Zhejiang Chinese Medical University,Zhejiang Chinese Medical University,Hangzhou 310053,China
Novel dual inhibitor for targeting PIM1 and FGFR1 kinases inhibits colorectal cancer growth in vitro and patient-derived xenografts in vivo
Fanxiang Yin;Ran Zhao;Dhilli Rao Gorja;Xiaorong Fu;Ning Lu;Hai Huang;Beibei Xu;Hanyong Chen;Jung-Hyun Shim;Kangdong Liu;Zhi Li;Kyle Vaughn Laster;Zigang Dong;Mee-Hyun Lee-Department of Pathophysiology,School of Basic Medical Sciences,Zhengzhou University,Zhengzhou 450001,China;China-US(Henan)Hormel Cancer Institute,Zhengzhou 450008,China;Translational Medical Center,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;The Hormel Institute,University of Minnesota,Austin,MN 55912,USA;Department of Biomedicine,Health&Life Convergencen Science,BK21 Four,College of Pharmacy,Mokpo National University,Jeonnam 58554,Republic of Korea;The Collaborative Innovation Center of Henan Province for Cancer Chemoprevention,Zhengzhou 450001,China;Department of General Surgery,the Affiliated Tumor Hospital of Zhengzhou University,Zhengzhou 450008,China;College of Korean Medicine,Dongshin University,Naju 58245,Republic of Korea
Cascade two-stage tumor re-oxygenation and immune re-sensitization mediated by self-assembled albumin-sorafenib nanoparticles for enhanced photodynamic immunotherapy
Zaigang Zhou;Jiashe Chen;Yu Liu;Chunjuan Zheng;Wenjuan Luo;Lele Chen;Shen Zhou;Zhiming Li;Jianliang Shen-State Key Laboratory of Ophthalmology,Optometry and Vision Science,School of Ophthalmology and Optometry,School of Biomedical Engineering,Wenzhou Medical University,Wenzhou 325027,China;Wenzhou Institute,University of Chinese Academy of Sciences,Wenzhou 325000,China;Department of the First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,China;School&Hospital of Stomatology,Wenzhou Medical University,Wenzhou 325027,China;Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine,Vision and Brain Health),Wenzhou 325000,China
机标中图分类号,由域田数据科技根据网络公开资料自动分析生成,仅供学习研究参考。