典型文献
Designing DNA cage-based immuno-fluorescence strategy for rapid diagnosis of clinical cervical cancer tissues
文献摘要:
Exploiting a tissue diagnosis method to abstain the involuted operating and consume valuable reagents while realizing high-speed and inexpensive pathological grading technology to supply a better scheme for cancer therapy is a significant method of cancers detection.A promising immuno-fluorescence strat-egy was rationally designed and synthesized by loading ruthenium complex into cervical cancer-targeted DNA-cage,which was well used to realize high-speed and inexpensive diagnosis of clinical cervical cancer tumor tissues avoiding the traditional multi-stage process,thus demonstrating high application potential in clinical pathological grading and surgical judgment.Moreover,it has been finding that Apts-DNA@Ru can enrichment in the tumor region,interestingly,no enrichment in normal cervical cancer tissue.It has the potential to realize the integration of in vivo diagnose and further synchronous treatment in the near future.Thence,this study demonstrates a strategy for integration of cancer-targeted DNA-cage and fluo-rescent RuPOP as alternative IHC reagents for next-generation more rapid convenient cancer detection.
文献关键词:
中图分类号:
作者姓名:
Juanjuan Li;Hongjie Luo;Xueqiong Zhu;Jianfu Zhao;Tianfeng Chen
作者机构:
Department of Oncology,The First Affiliated Hospital,and Department of Chemistry,Jinan University,Guangzhou 510632,China;Department of Obstetrics and Gynecology,The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University,Wenzhou 325000,China
文献出处:
引用格式:
[1]Juanjuan Li;Hongjie Luo;Xueqiong Zhu;Jianfu Zhao;Tianfeng Chen-.Designing DNA cage-based immuno-fluorescence strategy for rapid diagnosis of clinical cervical cancer tissues)[J].中国化学快报(英文版),2022(02):788-792
A类:
abstain,involuted,Apts,Thence,RuPOP
B类:
Designing,cage,immuno,fluorescence,strategy,rapid,diagnosis,clinical,cervical,tissues,Exploiting,method,operating,consume,valuable,reagents,while,realizing,high,speed,inexpensive,pathological,grading,technology,supply,better,scheme,therapy,significant,cancers,detection,promising,was,rationally,designed,synthesized,by,loading,ruthenium,complex,into,targeted,which,well,used,realize,tumor,avoiding,traditional,multi,stage,process,thus,demonstrating,application,potential,surgical,judgment,Moreover,has,been,finding,that,enrichment,region,interestingly,normal,It,integration,vivo,diagnose,further,synchronous,treatment,near,future,this,study,demonstrates,rescent,alternative,IHC,next,generation,more,convenient
AB值:
0.538169
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