典型文献
Extracellular vesicles in vascular remodeling
文献摘要：
Vascular remodeling contributes to the development of a variety of vascular diseases including hypertension and atherosclerosis.Phenotypic transformation of vascular cells,oxidative stress,inflammation and vascular calcification are closely associated with vascular remodeling.Extracellular vesicles(EVs)are naturally released from almost all types of cells and can be detected in nearly all body fluids including blood and urine.EVs affect vascular oxidative stress,inflammation,calcification,and lipid plaque formation;and thereby impact vascular remodeling in a variety of cardiovascular diseases.EVs may be used as biomarkers for diagnosis and prognosis,and therapeutic strategies for vascular remodeling and cardiovascular diseases.This review includes a comprehensive analysis of the roles of EVs in the vascular remodeling in vascular diseases,and the prospects of EVs in the diagnosis and treatment of vascular diseases.
文献关键词：
中图分类号：
作者姓名：
Chao Ye;Fen Zheng;Nan Wu;Guo-qing Zhu;Xiu-zhen Li
作者机构：
Key Laboratory of Targeted Intervention of Cardiovascular Disease,Collaborative Innovation Center for Cardiovascular Disease Translational Medicine,Department of Physiology,Nanjing Medical University,Nanjing 210029,China;Department of Cardiology,The Second Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China
文献出处：
引用格式：
[1]Chao Ye;Fen Zheng;Nan Wu;Guo-qing Zhu;Xiu-zhen Li-.Extracellular vesicles in vascular remodeling)[J].中国药理学报（英文版）,2022(09):2191-2201
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Extracellular,vesicles,remodeling,Vascular,contributes,development,variety,diseases,including,hypertension,atherosclerosis,Phenotypic,transformation,cells,oxidative,stress,inflammation,calcification,are,closely,associated,EVs,naturally,released,from,almost,types,can,be,detected,nearly,body,fluids,blood,urine,affect,lipid,plaque,thereby,impact,cardiovascular,may,used,biomarkers,diagnosis,prognosis,therapeutic,strategies,This,review,includes,comprehensive,analysis,roles,prospects,treatment
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0.503181
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