典型文献
A novel approach in preventing vascular leakage and angiogenesis in wet age-related macular degeneration
文献摘要:
Vascular leakage and angiogenesis in diseases: The vascular system carries blood throughout the body to supply oxygen and nutrients to tissues and remove waste from tissues. Dysfunction of the vascular system worsens many diseases. In this perspective, vascular function in blinding eye diseases, current therapies, and our developing approach will be introduced.
The blood vessels are composed of the monolayer of the endothelial cells, and the outer layer made by pericytes and smooth muscle cells provide structural support and shape to the vessel. Endothelial monolayers function as a barrier. The barrier function of endothelial monolayers controls plasma protein uptake and the infiltration of immune cells by regulating adherence of cell-cell junction. Vascular leakage causes unwanted plasma leak, accumulation of immune cells, and tissue inflammation.
文献关键词:
中图分类号:
作者姓名:
Kaori H.Yamada
作者机构:
Department of Pharmacology and Regenerative Medicine,Department of Ophthalmology and Visual Sciences,University of Illinois College of Medicine,Chicago,IL,USA
文献出处:
引用格式:
[1]Kaori H.Yamada-.A novel approach in preventing vascular leakage and angiogenesis in wet age-related macular degeneration)[J].中国神经再生研究(英文版),2022(08):1751-1752
A类:
B类:
novel,approach,preventing,vascular,leakage,angiogenesis,wet,related,macular,degeneration,Vascular,diseases,system,carries,blood,throughout,body,supply,oxygen,nutrients,tissues,remove,waste,from,Dysfunction,worsens,many,In,this,perspective,blinding,eye,current,therapies,our,developing,will,be,introduced,
The,vessels,are,composed,endothelial,cells,outer,made,by,pericytes,smooth,muscle,provide,structural,support,shape,Endothelial,monolayers,barrier,controls,plasma,protein,uptake,infiltration,immune,regulating,adherence,junction,causes,unwanted,accumulation,inflammation
AB值:
0.621843
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