Biomedical polymers have been extensively developed for promising applications in a lot of biomedical fields,such as ther-apeutic medicine delivery,disease detection and diagnosis,biosensing,regenerative medicine,and disease treatment.In this review,we summarize the most recent advances in the synthesis and application of biomedical polymers,and discuss the comprehensive understanding of their property-function relationship for corresponding biomedical applications.In particular,a few burgeoning bioactive polymers,such as peptide/biomembrane/microorganism/cell-based biomedical polymers,are also introduced and highlighted as the emerging biomaterials for cancer precision therapy.Furthermore,the foreseeable challenges and outlook of the development of more efficient,healthier and safer biomedical polymers are discussed.We wish this systemic and comprehensive review on highlighting frontier progress of biomedical polymers could inspire and promote new break-through in fundamental research and clinical translation.

Wei-Hai Chen;Qi-Wen Chen;Qian Chen;Chunyan Cui;Shun Duan;Yongyuan Kang;Yang Liu;Yun Liu;Wali Muhammad;Shiqun Shao;Chengqiang Tang;Jinqiang Wang;Lei Wang;Meng-Hua Xiong;Lichen Yin;Kuo Zhang;Zhanzhan Zhang;Xu Zhan;Jun Feng;Chanyou Gao;Zhen Gu;Chaoliang He;Jian Ji;Xiqun Jiang;Wenguang Liu;Zhuang Liu;Huisheng Peng;Youqing Shen;Linqi Shi;Xuemei Sun;Hao Wang;Jun Wang;Haihua Xiao;Fu-Jian Xu;Zhiyuan Zhong;Xian-Zheng Zhang;Xuesi-Chen

Key Laboratory of Biomedical Polymers of Ministry of Education&Department of Chemistry,Wuhan University,Wuhan 430072,China;Institute of Functional Nano&Soft Materials(FUNSOM),Jiangsu Key Laboratory for Carbon-Based Functional Materials&Devices,Soochow University,Suzhou 215123,China;School of Materials Science and Engineering,Tianjin Key Laboratory of Composite and Functional Materials,Tianjin University,Tianjin 300350,China;Key Laboratory of Biomedical Materials of Natural Macromolecules(Beijing University of Chemical Technology),Ministry of Education,Beijing Laboratory of Biomedical Materials,College of Materials Science and Engineering,Beijing University of Chemical Technology,Beijing 100029,China;MOE Key Laboratory of Macromolecular Synthesis and Functionalization,Department of Polymer Science and Engineering,Zhejiang University,Hangzhou 310027,China;State Key Laboratory of Medicinal Chemical Biology,Key Laboratory of Functional Polymer Materials of Ministry of Education,College of Chemistry,Nankai University,Tianjin 300071,China;Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China;Jinhua Institute of Zhejiang University,Jinhua 321299,China;Zhejiang Key Laboratory of Smart BioMaterials and Center for Bionanoengineering,College of Chemical and Biological Engineering,Zhejiang University,Hangzhou 310027,China;ZJU-Hangzhou Global Scientific and Technological Innovation Center,Hangzhou 311215,China;State Key Laboratory of Molecular Engineering of Polymers,Department of Macromolecular Science and Laboratory of Advanced Materials,Fudan University,Shanghai 200438,China;CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety,CAS Center for Excellence in Nano-science,National Center for Nanoscience and Technology(NCNST),Beijing 100190,China;School of Biomedical Sciences and Engineering,Guangzhou International Campus,South China University of Technology,Guangzhou 510006,China;Institute of Functional Nano and Soft Materials(FUNSOM),Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices,Collaborative Innovation Center of Suzhou Nano Science&Technology,Soochow University,Suzhou 215123,China;Department of Polymer Science and Engineering,College of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210093,China;CAS Key Laboratory of Polymer Ecomaterials,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China;Beijing National Laboratory for Molecular Sciences,State Key Laboratory of Polymer Physics and Chemistry,Institute of Chemistry,Chinese Academy of Sciences,Beijing 100190,China;Biomedical Polymers Laboratory,College of Chemistry,Chemical Engineering and Materials Science, and State Key Laboratory of Radiation Medicine and Protection,Soochow University,Suzhou 215123,China;College of Pharmaceutical Sciences,Soochow University,Suzhou 215123,China

中国科学:化学（英文版）

[1]Wei-Hai Chen;Qi-Wen Chen;Qian Chen;Chunyan Cui;Shun Duan;Yongyuan Kang;Yang Liu;Yun Liu;Wali Muhammad;Shiqun Shao;Chengqiang Tang;Jinqiang Wang;Lei Wang;Meng-Hua Xiong;Lichen Yin;Kuo Zhang;Zhanzhan Zhang;Xu Zhan;Jun Feng;Chanyou Gao;Zhen Gu;Chaoliang He;Jian Ji;Xiqun Jiang;Wenguang Liu;Zhuang Liu;Huisheng Peng;Youqing Shen;Linqi Shi;Xuemei Sun;Hao Wang;Jun Wang;Haihua Xiao;Fu-Jian Xu;Zhiyuan Zhong;Xian-Zheng Zhang;Xuesi-Chen-.Biomedical polymers:synthesis,properties,and applications)[J].中国科学:化学（英文版）,2022(06):1010-1075

biomembrane

Biomedical,polymers,synthesis,properties,applications,have,been,extensively,developed,promising,lot,biomedical,fields,such,apeutic,medicine,delivery,disease,detection,diagnosis,biosensing,regenerative,treatment,In,this,review,we,summarize,most,recent,advances,comprehensive,understanding,their,property,function,relationship,corresponding,particular,few,burgeoning,bioactive,peptide,microorganism,cell,are,also,introduced,highlighted,emerging,biomaterials,cancer,precision,therapy,Furthermore,foreseeable,challenges,outlook,development,efficient,healthier,safer,discussed,We,wish,systemic,highlighting,frontier,progress,could,inspire,promote,new,break,through,fundamental,research,clinical,translation

0.639529