典型文献
An endoparasitoid uses its egg surface proteins to regulate its host immune response
文献摘要：
With proteomic analysis,we identified 379 egg surface proteins from an en-doparasitoid,Cotesia chilonis.Proteins containing conserved enzymatic domains con-stitute a large proportion of egg surface components.Some proteins,such as superoxi-dase dismutase,homolog of C.rubecula 32-kDa protein,and immunoevasive protein-2A,are classical parasitism factors that have known functions in host immunity regulation.Melanization assays revealed that a novel egg surface protein,C.chilonis egg surface ser-pin domain-containing protein had the same function as a C.chilonis venom serpin,as both suppressed host melanization in a dose-dependent manner.C.chilonis egg surface serpin domain-containing protein is mainly transcribed in C.chilonis oocytes with fol-licular cells,and it is located on both the anterior and posterior sides of the mature egg surface.Additionally,we used LC-MS/MS to identify 586 binding proteins sourced from C.suppressalis plasma located on the eggshell surface of C.chilonis,which included some immunity-related proteins.These results not only indicate that C.chilonis uses its egg sur-face proteins to reduce the immune response of its host but also imply that endoparasitoid egg surface proteins might be a new parasitism factor involved in host immune regulation.
文献关键词：
中图分类号：
作者姓名：
Zi-Wen Teng;Hui-Zi Wu;Xin-Hai Ye;Qi Fang;Hong-Xu Zhou;Gong-Yin Ye
作者机构：
China-Australia Cooperation Base of Crop Health and Invasive Species,China-Australia Joint Institute of Agricultural and Environmental Health,College of Plant Health and Medicine,Qingdao Agricultural University,Qingdao,Shandong Province,China;State Key Lab-oratory of Rice Biology,Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insects,Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province,Institute of Insect Sciences,Zhejiang University,Hangzhou,China
文献出处：
引用格式：
[1]Zi-Wen Teng;Hui-Zi Wu;Xin-Hai Ye;Qi Fang;Hong-Xu Zhou;Gong-Yin Ye-.An endoparasitoid uses its egg surface proteins to regulate its host immune response)[J].中国昆虫科学（英文版）,2022(04):1030-1046
A类：
endoparasitoid,doparasitoid,Cotesia,superoxi,rubecula,immunoevasive,Melanization,melanization,licular
B类：
An,uses,its,surface,proteins,regulate,host,immune,response,With,proteomic,analysis,we,identified,from,chilonis,Proteins,containing,conserved,enzymatic,domains,stitute,large,proportion,components,Some,such,dase,dismutase,homolog,kDa,2A,are,classical,parasitism,factors,that,have,known,functions,immunity,regulation,assays,revealed,novel,had,same,venom,serpin,both,suppressed,dose,dependent,manner,mainly,transcribed,oocytes,fol,cells,located,anterior,posterior,sides,mature,Additionally,used,LC,identify,binding,sourced,suppressalis,plasma,eggshell,which,included,some,related,These,results,not,only,indicate,reduce,but,also,imply,might,new,involved
AB值：
0.455116
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
