典型文献
The RECEPTOR-LIKE PROTEIN53 immune complex associates with LLG1 to positively regulate plant immunity
文献摘要：
Pattern recognition receptors (PRRs) sense li-gands in pattern-triggered immunity (PTI). Plant PRRs include numerous receptor-like proteins (RLPs), but many RLPs remain functionally un-characterized. Here, we examine an Arabidopsis thaliana RLP, RLP53, which positively regulates immune signaling. Our forward genetic screen for suppressors of enhanced disease resistance1 (edr1) identified a point mutation in RLP53 that fully suppresses disease resistance and mildew-induced cell death in edr1 mutants. The rlp53 mutants showed enhanced susceptibility to viru-lent pathogens, including fungi, oomycetes, and bacteria, indicating that RLP53 is important for plant immunity. The ectodomain of RLP53 con-tains leucine-rich repeat (LRR) motifs. RLP53 constitutively associates with the LRR receptor-like kinase SUPPRESSOR OF BRASSINOSTE-ROID INSENSITIVE1-ASSOCIATED KINASE (BAK1)-INTERACTING RECEPTOR KINASE1 (SOBIR1) and interacts with the co-receptor BAK1 in a pathogen-induced manner. The double mutation sobir1-12 bak1-5 suppresses edr1-mediated disease resistance, suggesting that EDR1 negatively regulates PTI modulated by the RLP53–SOBIR1–BAK1 complex. Moreover, the glycosylphosphatidylinositol (GPI)-anchored protein LORELEI-LIKE GPI-ANCHORED PRO-TEIN1 (LLG1) interacts with RLP53 and mediates RLP53 accumulation in the plasma membrane. We thus uncovered the role of a novel RLP and its associated immune complex in plant defense responses and revealed a potential new mecha-nism underlying regulation of RLP immune func-tion by a GPI-anchored protein.
文献关键词：
中图分类号：
作者姓名：
Renjie Chen;Pengwei Sun;Guitao Zhong;Wei Wang;Dingzhong Tang
作者机构：
State Key Laboratory of Ecological Control of Fujian-Taiwan Crop Pests,Key Laboratory of Ministry of Education for Genetics,Breeding and Multiple Utilization of Crops,Plant Immunity Center,Fujian Agriculture and Forestry University,Fuzhou 350002,China;Institute of Genetics and Developmental Biology,the Chinese Academy of Sciences,Beijing 100101,China;College of Life Sciences,University of Chinese Academy of Sciences,Beijing 100049,China;Ministerial and Provincial Joint Innovation Centre for Safety Production of Cross-Strait Crops,Fujian Agriculture and Forestry University,Fuzhou 350002,China
文献出处：
引用格式：
[1]Renjie Chen;Pengwei Sun;Guitao Zhong;Wei Wang;Dingzhong Tang-.The RECEPTOR-LIKE PROTEIN53 immune complex associates with LLG1 to positively regulate plant immunity)[J].植物学报（英文版）,2022(09):1833-1846
A类：
RECEPTOR,PROTEIN53,LLG1,gands,RLPs,RLP53,resistance1,edr1,rlp53,oomycetes,ectodomain,BRASSINOSTE,ROID,INSENSITIVE1,ASSOCIATED,KINASE,INTERACTING,KINASE1,SOBIR1,sobir1,bak1,EDR1,LORELEI,ANCHORED,TEIN1
B类：
LIKE,immune,complex,associates,positively,plant,immunity,Pattern,recognition,receptors,PRRs,sense,pattern,triggered,PTI,Plant,include,numerous,like,proteins,but,many,remain,functionally,characterized,Here,examine,Arabidopsis,thaliana,which,regulates,signaling,Our,forward,genetic,screen,suppressors,enhanced,disease,identified,point,mutation,that,fully,suppresses,mildew,induced,cell,death,mutants,showed,susceptibility,viru,lent,pathogens,including,fungi,bacteria,indicating,important,tains,leucine,rich,repeat,LRR,motifs,constitutively,kinase,SUPPRESSOR,OF,BAK1,interacts,manner,double,mediated,suggesting,negatively,modulated,by,Moreover,glycosylphosphatidylinositol,GPI,anchored,mediates,accumulation,plasma,membrane,We,thus,uncovered,role,novel,its,associated,defense,responses,revealed,potential,new,mecha,nism,underlying,regulation
AB值：
0.419523
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