典型文献
Complement use of Chinese herbal medicine after percuta-neous coronary intervention: a prospective observational study
文献摘要：
BACKGROUND Chinese herbal medicine is widely used as a complement or alternative treatment in coronary artery disease (CAD) patients after percutaneous coronary intervention (PCI) in China. We compared the incidence of the major adverse cardi-ovascular event (MACE) of CAD patients with or without the complement use of Chinese herbal medicine after PCI. METHODS In this prospective, observational study that was conducted from September 2016 to August 2019 in Fuwai Hospital (China), we followed up consecutive patients who received PCI treatment for two years. MACE was defined as the composite all-cause mortality, revascularization, and myocardial infarction (MI) and was compared between those using (integrative medicine group) or those not using Chinese herbal medicine as an additional treatment to standard Western medicine, with unadjusted (Kaplan-Meier curves) and risk-adjusted (multivariable Cox regression) analyses. RESULTS A total of 5942 patients after PCI were enrolled in this study, and 5453 patients were included in the final analysis (4189 [76.8％] male; mean age: 61.9 ± 9.9％ years). During the follow-ups, 2932 (53.8％) patients used only Western medicine while 2521(46.2％) patients had used Chinese herbal medicine as an additional treatment to standard Western medicine. Patients in the integrative medicine group (IM group) were older than the Western medicine group (WM group), had more females and less pre-vious MI. The incidence of MACE was 15.3％ (449/2932) in WM group and 11.54％ (291/2521) in IM group. Cox regression ana-lysis showed that cumulative incidence of MACE was 27％ lower in patients of the IM group than those in WM group (hazard ra-tio = 0.73; 95％ CI: 0.63-0.85; P < 0.0001). CONCLUSIONS For CAD patients after PCI treatment, complement use of Chinese herbal medicine is associated with a lower 2-year MACE incidence. Randomized prospective studies are warranted to provide higher levels of benefit evidence in these pa-tients.
文献关键词：
中图分类号：
作者姓名：
Si-Yu YAN;Wei-Xian YANG;Pei-Pei LU;Xuan-Tong GUO;Cai-Xia GUO;Yan-Ni SU;Li-Hong MA
作者机构：
Chinese Academy of Medical Sciences&Peking Union Medical College Fuwai Hospital,Xicheng District,Beijing,China
文献出处：
引用格式：
[1]Si-Yu YAN;Wei-Xian YANG;Pei-Pei LU;Xuan-Tong GUO;Cai-Xia GUO;Yan-Ni SU;Li-Hong MA-.Complement use of Chinese herbal medicine after percuta-neous coronary intervention: a prospective observational study)[J].老年心脏病学杂志（英文版）,2022(09):696-704
A类：
cardi,ovascular
B类：
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AB值：
0.437066
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