典型文献
Four-protein model for predicting prognostic risk of lung cancer
文献摘要：
Patients with lung cancer at the same stage may have markedly different overall outcome and a lack of specific biomarker to predict lung cancer outcome.Heat-shock protein 90 β(HSP90β)is overexpressed in various tumor cells.In this study,the ELISA results of HSP90β combined with CEA,CA125,and CYFRA21-1 were used to construct a recursive partitioning decision tree model to establish a four-protein diagnostic model and predict the survival of patients with lung cancer.Survival analysis showed that the recursive partitioning decision tree could distinguish the prognosis between high-and low-risk groups.Results suggested that the joint detection of HSP90β,CEA,CA125,and CYFRA21-1 in the peripheral blood of patients with lung cancer is plausible for early diagnosis and prognosis prediction of lung cancer.
文献关键词：
中图分类号：
作者姓名：
Xiang Wang;Minghui Wang;Lin Feng;Jie Song;Xin Dong;Ting Xiao;Shujun Cheng
作者机构：
State Key Laboratory of Molecular Oncology,Department of Etiology and Carcinogenesis,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China;Department of Clinical Laboratory,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China
文献出处：
引用格式：
[1]Xiang Wang;Minghui Wang;Lin Feng;Jie Song;Xin Dong;Ting Xiao;Shujun Cheng-.Four-protein model for predicting prognostic risk of lung cancer)[J].医学前沿,2022(04):618-626
A类：
B类：
Four,protein,model,predicting,prognostic,risk,lung,cancer,Patients,same,stage,may,have,markedly,different,overall,outcome,lack,specific,biomarker,Heat,shock,HSP90,overexpressed,various,tumor,cells,In,this,study,results,combined,CEA,CA125,CYFRA21,were,used,construct,recursive,partitioning,decision,tree,establish,four,diagnostic,survival,patients,Survival,analysis,showed,that,could,distinguish,prognosis,between,high,low,groups,Results,suggested,joint,detection,peripheral,blood,plausible,early,diagnosis,prediction
AB值：
0.594655
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