典型文献
SARS-CoV-2 variants,immune escape,and countermeasures
文献摘要：
Coronavirus disease 2019(COVID-19)has become a global pandemic disease.SARS-CoV-2 variants have aroused great concern and are expected to continue spreading.Although many countries have promoted roll-out vaccination,the immune barrier has not yet been fully established,indicating that populations remain susceptible to infection.In this review,we summarize the literature on variants of concern and focus on the changes in their transmissibility,pathogenicity,and resistance to the immunity constructed by current vaccines.Furthermore,we analyzed relationships between variants and breakthrough infections,as well as the paradigm of new variants in countries with high vaccination rates.Terminating transmission,continuing to strengthen variant surveillance,and combining nonpharmaceutical intervention measures and vaccines are necessary to control these variants.
文献关键词：
中图分类号：
作者姓名：
Yi Zhang;Haocheng Zhang;Wenhong Zhang
作者机构：
Department of Infectious Diseases,National Medical Center for Infectious Diseases,Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response,Huashan Hospital Fudan University Shanghai 200040 China;State Key Laboratory of Genetic Engineering and Institute of Biostatistics,School of Life Sciences,Fudan University,Shanghai 200040,China
文献出处：
引用格式：
[1]Yi Zhang;Haocheng Zhang;Wenhong Zhang-.SARS-CoV-2 variants,immune escape,and countermeasures)[J].医学前沿,2022(02):196-207
A类：
Terminating,nonpharmaceutical
B类：
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AB值：
0.65762
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