典型文献
SARS-CoV-2 infection induces testicular injury in Rhesus macaque
文献摘要：
Dear Editor,
COVID-19 is caused by the severe acute respiratory syndrome coro-navirus 2(SARS-CoV-2),which is the seventh coronavirus known to infect humans.The COVID-19 pandemic has spread to more than 200 countries,with more than 600 million confirmed cases and over 6.5 million deaths as of September 2022,posing a huge challenge to global public health.Clinical symptoms of COVID-19 have been observed,including fever,cough,fatigue,diarrhea,vomiting,and even neurologic symptoms,and the SARS-CoV-2 has been detected in multiple organs in patients.The receptor-mediated binding and entry is the key stage of viral infection of host cells and humans,and human angiotensin-converting enzyme 2(ACE2)is the specific receptor mediating the entry of SARS-CoV-2(Zhou et al.,2020).It has demonstrated that the expression of the ACE2 in the testis of the male reproductive system is high(Li et al.,2020),suggesting that the male reproductive system may be vulnerable to SARS-CoV-2 infection and the ACE2 may regulate testicular function and play a role in sperm production.
文献关键词：
中图分类号：
作者姓名：
Mengying Liang;Wanbo Tai;Yunyun Wang;Yulong Dai;Yanfeng Yao;Juan Min;Yiwu Zhou;Liang Liu;Chao Shan;Han Xia;Zhiming Yuan
作者机构：
Key Laboratory of Special Pathogens and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan,430061,China;University of Chinese Academy of Sciences,Beijing 100049,China;Institute of Infectious Diseases,Shenzhen Bay Laboratory,Shenzhen,518069,China;Department of Forensic Medicine,Tongji Medical College of Huazhong University of Science and Technology,Wuhan,430030,China;Wuhan National Biosafety Laboratory,Chinese Academy of Sciences,Wuhan,430073,China;The Core Facility and Technical Support,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan,430061,China;State Key Laboratory of Virology,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan,430061 China
文献出处：
引用格式：
[1]Mengying Liang;Wanbo Tai;Yunyun Wang;Yulong Dai;Yanfeng Yao;Juan Min;Yiwu Zhou;Liang Liu;Chao Shan;Han Xia;Zhiming Yuan-.SARS-CoV-2 infection induces testicular injury in Rhesus macaque)[J].中国病毒学,2022(06):934-937
A类：
Rhesus,
COVID
B类：
SARS,CoV,infection,induces,testicular,injury,macaque,Dear,Editor,caused,by,severe,acute,respiratory,syndrome,which,seventh,coronavirus,known,humans,pandemic,has,spread,more,than,countries,million,confirmed,cases,over,deaths,September,posing,huge,challenge,global,public,health,Clinical,symptoms,have,been,observed,including,fever,cough,fatigue,diarrhea,vomiting,neurologic,detected,multiple,organs,patients,receptor,mediated,binding,entry,key,stage,viral,host,cells,angiotensin,converting,enzyme,ACE2,specific,mediating,Zhou,It,demonstrated,that,expression,testis,male,reproductive,system,high,Li,suggesting,may,vulnerable,regulate,function,play,role,sperm,production
AB值：
0.584058
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
