典型文献
Viral metagenomics reveals diverse viruses in the fecal samples of children with diarrhea
文献摘要：
Diarrhea is the third leading cause of death in developing countries in children under the age of five.About half a million children die of diarrhea every year,most of which in developing countries.Viruses are the main pathogen of diarrhea.In China,the fecal virome of children with diarrhea has been rarely studied.Using an unbiased viral metagenomics approach,we analyzed the fecal virome in children with diarrhea.Many DNA or RNA viruses associated with diarrhea identified in those fecal samples were mainly from six families of Adenoviridae,Astro-viridae,Caliciviridae,Parvoviridae,Picomaviridae,and Reoviridae.Among them,the family of Caliciviridae accounts for the largest proportion of 78.42％,following with Adenoviridae(8.94％)and Picomaviridae(8.36％).In addition to those diarrhea-related viruses that have already been confirmed to cause human diarrhea,the viruses not associated with diarrhea were also identified including anellovirus and picobirnavirus.This study increased our understanding of diarrheic children fecal virome and provided valuable information for the prevention and treatment of viral diarrhea in this area.
文献关键词：
中图分类号：
作者姓名：
Shixing Yang;Yumin He;Ju Zhang;Dianqi Zhang;Yan Wang;Xiang Lu;Xiaochun Wang;Quan Shen;Likai Ji;Hongyan Lu;Wen Zhang
作者机构：
Department of Pediatrics,Affiliated Hospital of Jiangsu University,Zhenjiang,212013,China;School of Medicine,Jiangsu University,Zhenjiang,212013,China
文献出处：
引用格式：
[1]Shixing Yang;Yumin He;Ju Zhang;Dianqi Zhang;Yan Wang;Xiang Lu;Xiaochun Wang;Quan Shen;Likai Ji;Hongyan Lu;Wen Zhang-.Viral metagenomics reveals diverse viruses in the fecal samples of children with diarrhea)[J].中国病毒学,2022(01):82-93
A类：
virome,Adenoviridae,Astro,viridae,Caliciviridae,Parvoviridae,Picomaviridae,anellovirus,picobirnavirus
B类：
Viral,metagenomics,reveals,diverse,viruses,fecal,samples,children,diarrhea,Diarrhea,third,leading,cause,death,developing,countries,five,About,half,million,every,year,most,which,Viruses,pathogen,In,China,has,been,rarely,studied,Using,unbiased,viral,approach,analyzed,Many,associated,identified,those,were,mainly,from,six,families,Reoviridae,Among,them,family,accounts,largest,proportion,following,addition,related,that,have,already,confirmed,human,not,also,including,This,study,increased,our,understanding,diarrheic,provided,valuable,information,prevention,treatment,this,area
AB值：
0.44906
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