典型文献
Genetic pathogenesis of acephalic spermatozoa syndrome:past,present,and future
文献摘要：
Acephalic spermatozoa syndrome(ASS)is one of the most severe spermatogenic failures of all infertility in men.The cognition of ASS has experienced a tortuous process.Over the past years,with the in-depth understanding of spermatogenesis and the emergence of new genetic research technologies,the unraveling of the genetic causes of spermatogenic failure has become highly active.From these advances,we established a genetic background and made significant progress in the discovery of the genetic causes of ASS.It is important to identify pathogenic genes and mutations in ASS to determine the biological reasons for the occurrence of the disease as well as provide genetic diagnosis and treatment strategies for patients with this syndrome.In this review,we enumerate various technological developments,which have made a positive contribution to the discovery of candidate genes for ASS from the past to the present.Simultaneously,we summarize the known genetic etiology of this phenotype and the clinical outcomes of treatments in the present.Furthermore,we propose perspectives for further study and application of genetic diagnosis and assisted reproductive treatment in the future.
文献关键词：
中图分类号：
作者姓名：
Yu Wang;Ming-Fei Xiang;Na Zheng;Yun-Xia Cao;Fu-Xi Zhu
作者机构：
Reproductive Medicine Center,Department of Obstetrics and Gynecology,The First Affiliated Hospital of Anhui Medical University,Hefei 230022,China;NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract,Anhui Medical University,Hefei 230032,China;Key Laboratory of Population Health Across Life Cycle,Anhui Medical University,Ministry of Education of the People's Republic of China,Hefei 230032,China;Anhui Province Key Laboratory of Reproductive Health and Genetics,Anhui Medical University,Hefei 230022,China
文献出处：
引用格式：
[1]Yu Wang;Ming-Fei Xiang;Na Zheng;Yun-Xia Cao;Fu-Xi Zhu-.Genetic pathogenesis of acephalic spermatozoa syndrome:past,present,and future)[J].亚洲男性学杂志（英文版）,2022(03):231-237
A类：
acephalic,Acephalic,enumerate
B类：
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AB值：
0.553577
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