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典型文献
Clinical impact and mechanisms of hepatitis B virus infection concurrent with non-alcoholic fatty liver disease
文献摘要:
Chronic hepatitis B (CHB) virus infection is an important threat to global health despite the administration of vaccines and the use of antiviral treatments. In recent years, as the prevalence of obesity and metabolic syndrome has increased, non-alcoholic fatty liver disease (NAFLD) in patients with CHB has become more common. Both diseases can lead to liver fibrosis and even hepatocellular carcinoma, but the risk of dual etiology, outcome, and CHB combined with NAFLD is not fully elucidated. In this review, we assess the overlapping prevalence of NAFLD and CHB, summarize recent studies of clinical and basic research related to potential interactions, and evaluate the progressive changes of treatments for CHB patients with NAFLD. This review increases the understanding of the relationship and mechanisms of interaction between steatosis and hepatitis B virus infection, and it provides new strategies for the future clinical management and treatment of CHB combined with NAFLD.
文献关键词:
Chronic hepatitis B;Non-alcoholic fatty liver disease;Steatosis;Mechanism
作者姓名:
Tong Xin;Song Yu;Yin Shengxia;Wang Jian;Huang Rui;Wu Chao;Shi Junping;Li Jie
作者机构:
Department of Infectious Diseases, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu 210008, China;Institute of Viruses and Infectious Diseases, Nanjing University, Nanjing, Jiangsu 210008, China;Department of Hepatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China;Department of Hepatology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang 310015, China
引用格式:
[1]Tong Xin;Song Yu;Yin Shengxia;Wang Jian;Huang Rui;Wu Chao;Shi Junping;Li Jie-.Clinical impact and mechanisms of hepatitis B virus infection concurrent with non-alcoholic fatty liver disease)[J].中华医学杂志(英文版),2022(14):1653-1663
A类:
Steatosis
B类:
Clinical,impact,mechanisms,hepatitis,virus,infection,concurrent,alcoholic,fatty,liver,Chronic,CHB,important,threat,global,health,despite,administration,vaccines,use,antiviral,treatments,In,recent,years,prevalence,obesity,metabolic,syndrome,has,increased,NAFLD,patients,become,more,common,Both,diseases,can,lead,fibrosis,even,hepatocellular,carcinoma,but,risk,dual,etiology,outcome,combined,not,fully,elucidated,this,review,assess,overlapping,summarize,studies,clinical,basic,research,related,potential,interactions,evaluate,progressive,changes,This,increases,understanding,relationship,between,steatosis,provides,new,strategies,future,management,Non,Mechanism
AB值:
0.555075
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