典型文献
The advanced development of molecular targeted therapy for hepatocellular carcinoma
文献摘要:
Hepatocellular carcinoma (HCC), one of the most common malignant tumors in China, severely threatens the life and health of patients. In recent years, precision medicine, clinical diagnoses, treatments, and innovative research have led to important breakthroughs in HCC care. The discovery of new biomarkers and the promotion of liquid biopsy technologies have greatly facilitated the early diagnosis and treatment of HCC. Progress in targeted therapy and immunotherapy has provided more choices for precise HCC treatment. Multiomics technologies, such as genomics, transcriptomics, and metabolomics, have enabled deeper understanding of the occurrence and development mechanisms, heterogeneity, and genetic mutation characteristics of HCC. The continued promotion and accurate typing of HCC, accurate guidance of treatment, and accurate prognostication have provided more treatment opportunities and prolonged survival timelines for patients with HCC. Innovative HCC research providing an in-depth understanding of the biological characteristics of HCC will be translated into accurate clinical practices for the diagnosis and treatment of HCC.
文献关键词:
中图分类号:
作者姓名:
Tao Yan;Lingxiang Yu;Ning Zhang;Caiyun Peng;Guodong Su;Yi Jing;Linzhi Zhang;Tong Wu;Jiamin Cheng;Qian Guo;Xiaoliang Shi;Yinying Lu
作者机构:
Comprehensive Liver Cancer Center,the 5th Medical Center of Chinese PLA General Hospital,Beijing 100039,China;The Second School of Clinical Medicine,Southern Medical University,Guangzhou 510515,China;The Second Department of Hepatobiliary Surgery,Senior Department of Hepatology,the 5th Medical Center of Chinese PLA General Hospital,Beijing 100039,China;Shanghai OrigiMed Co.,Ltd.,Shanghai 201112,China;National Clinical Medical Research Center for Infectious Diseases,the 5th Medical Center of Chinese PLA General Hospital,Beijing 100039,China
文献出处:
引用格式:
[1]Tao Yan;Lingxiang Yu;Ning Zhang;Caiyun Peng;Guodong Su;Yi Jing;Linzhi Zhang;Tong Wu;Jiamin Cheng;Qian Guo;Xiaoliang Shi;Yinying Lu-.The advanced development of molecular targeted therapy for hepatocellular carcinoma)[J].癌症生物学与医学(英文版),2022(06):802-817
A类:
Multiomics,prognostication
B类:
advanced,development,molecular,targeted,hepatocellular,carcinoma,Hepatocellular,HCC,one,most,common,malignant,tumors,China,severely,threatens,life,health,patients,recent,years,precision,medicine,clinical,diagnoses,treatments,innovative,research,have,important,breakthroughs,care,discovery,new,biomarkers,promotion,liquid,biopsy,technologies,greatly,facilitated,early,diagnosis,Progress,immunotherapy,has,provided,more,choices,precise,such,genomics,transcriptomics,metabolomics,enabled,deeper,understanding,occurrence,mechanisms,heterogeneity,genetic,mutation,characteristics,continued,accurate,typing,guidance,opportunities,prolonged,survival,timelines,Innovative,providing,depth,biological,will,be,translated,into,practices
AB值:
0.595282
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