典型文献
Artificially regulated synthesis of nanocrystals in live cells
文献摘要:
Live cells,as reservoirs of biochemical reactions,can serve as amazing integrated chemical plants where precursor formation,nucleation and growth of nanocrystals,and functional assembly,can be carried out accurately following an artificial program.It is crucial but challenging to deliberately direct intracellular pathways to synthesize desired nanocrystals that cannot be produced naturally in cells,because the relevant reactions exist in different spatiotemporal dimensions and will never encounter each other spontaneously.This article summarizes the progress in the introduction of inorganic functional nanocrystals into live cells via the'artificially regulated space-time-coupled live-cell synthesis'strategy.We also describe ingenious bio-applications of nanocrystal-cell systems,and quasi-biosynthesis strategies expanded from live-cell synthesis.Artificially regulated live-cell synthesis—which involves the interdisciplinary application of biology,chemistry,nanoscience and medicine—will enable researchers to better exploit the unanticipated potentialities of live cells and open up new directions in synthetic biology.
文献关键词:
中图分类号:
作者姓名:
An-An Liu;En-Ze Sun;Zhi-Gang Wang;Shu-Lin Liu;Dai-Wen Pang
作者机构:
State Key Laboratory of Medicinal Chemical Biology,Tianjin Key Laboratory of Biosensing and Molecular Recognition,Frontiers Science Center for New Organic Matter,Research Center for Analytical Sciences,College of Chemistry,School of Medicine,Frontiers Science Center for Cell Responses,Nankai University,Tianjin 300071,China;College of Chemistry and Molecular Sciences,Wuhan University,Wuhan 430072,China
文献出处:
引用格式:
[1]An-An Liu;En-Ze Sun;Zhi-Gang Wang;Shu-Lin Liu;Dai-Wen Pang-.Artificially regulated synthesis of nanocrystals in live cells)[J].国家科学评论(英文版),2022(06):184-194
A类:
Artificially,potentialities
B类:
regulated,nanocrystals,live,cells,Live,reservoirs,biochemical,reactions,serve,amazing,integrated,plants,where,precursor,formation,nucleation,growth,functional,assembly,carried,out,accurately,following,program,It,crucial,but,challenging,deliberately,intracellular,pathways,synthesize,desired,that,cannot,produced,naturally,because,relevant,exist,different,spatiotemporal,dimensions,will,never,encounter,each,other,spontaneously,This,article,summarizes,progress,introduction,inorganic,into,via,artificially,space,coupled,strategy,We,also,describe,ingenious,applications,systems,quasi,biosynthesis,strategies,expanded,from,which,involves,interdisciplinary,biology,chemistry,nanoscience,medicine,enable,researchers,better,exploit,unanticipated,open,new,directions,synthetic
AB值:
0.623182
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