Background This study aimed to explore the associations of factors with in-hospital mortality in sepsis with MRSA infection based on the MIMIC-Ⅳ database.Methods All sepsis pa-tients with MRSA infection were included.Multivariate regression analysis was applied to identify predictive factors.Models were applied to explore the relationship between the factors and in-hospital mortality after adjusting potential cofounders.Results A total of 157 patients were included inclu-ding a survivor group(n=111)and a non-survivor group(n=46)were included.RDW was identi-fied as an independent factor with in-hospital mortality.A smooth fitting curve for a positive linear re-lationship between RDW and in-hospital mortality was constructed.The area under the ROC curve(AUC)was 0.652 with a sensitivity of 0.565 and a specificity of 0.676.The optimal cut-off value of RDW was 16.55.Compared with SOFA and APACHE Ⅱ scores,RDW had a better predictive per-formance.Conclusion RDW was associated with clinical outcomes in sepsis with MRSA infection.

Song Kun;Song Yaqin;Ding Ning;Li Changluo

Department of Emergency Medicine,The Affiliated Changsha Central Hospital,Hengyang Medical School,University of South China

实用休克杂志（中英文）

[1]Song Kun;Song Yaqin;Ding Ning;Li Changluo-.Red blood cell distribution width is associated with in-hospital mortality in sepsis with MRSA infection in MIMIC-Ⅳ)[J].实用休克杂志（中英文）,2022(06):377-384

cofounders

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