典型文献
Disability-adjusted life years and the trends of the burden of colorectal cancer: a population-based study in Shanghai, China during 2002 to 2016
文献摘要：
Background::Colorectal cancer (CRC) still ranks the top in morbidity and mortality of cancers worldwide, posing a huge threat and burden to the society. We aimed to determine the age-standardized incidence, mortality, and disability-adjusted life years (DALYs) of CRC and explore potential changes in the temporal trends of the CRC burden in Shanghai during 2002 to 2016.Methods::The cancer statistics and demographics were obtained from the Cancer Registry and the Statistics Bureau of Pudong New Area, respectively. Data from 2002 to 2016 were included and analyzed retrospectively. DALYs were calculated using DisMod and the age-standardized rates (ASRs) were obtained according to Segi world standard population. Joinpoint regression was used to measure the trends in CRC incidence and to estimate the annual percent change.Results::The increasing trend of CRC ASR incidence halted after 2014, coinciding with the introduction of the Shanghai CRC screening program. The ASRs of mortality and DALYs increased, at 0.42% (
P < 0.05) and 4.07% (
P < 0.001) per year, respectively, which were mainly driven by men and individuals aged above the CRC screening program target.
Conclusions::The disease burden of CRC in Shanghai remains serious, especially among men, and individuals aged >74 years. The benefits of the screening program have been partially proven by the ASRs of CRC incidence, providing important insights into better and wider application of screening programs.
文献关键词：
Colorectal cancer;Disability-adjusted life years;Disease burden;Regression analysis;Screening program
中图分类号：
作者姓名：
Zhong Wei;Chen Liping;Li Xiaopan;Chen Yichen;Zhang Yao;Guo Canjie;Shen Yufeng;Chen Huimin
作者机构：
Department of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, State Key Laboratory for Oncogenes and Related Genes, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200001, China;Department of Internal Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200001, China;Department of Health Management Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China;Center for Disease Control and Prevention, Fudan University Pudong Institute of Preventive Medicine, Shanghai 200136, China
文献出处：
引用格式：
[1]Zhong Wei;Chen Liping;Li Xiaopan;Chen Yichen;Zhang Yao;Guo Canjie;Shen Yufeng;Chen Huimin-.Disability-adjusted life years and the trends of the burden of colorectal cancer: a population-based study in Shanghai, China during 2002 to 2016)[J].中华医学杂志（英文版）,2022(24):2950-2955
A类：
Pudong,DisMod,ASRs,halted
B类：
Disability,adjusted,life,years,trends,burden,colorectal,population,study,Shanghai,China,during,Background,Colorectal,CRC,still,ranks,top,morbidity,mortality,cancers,worldwide,posing,huge,threat,society,We,aimed,determine,standardized,incidence,disability,DALYs,explore,potential,changes,temporal,Methods,statistics,demographics,were,obtained,from,Cancer,Registry,Statistics,Bureau,New,Area,respectively,Data,included,analyzed,retrospectively,calculated,using,rates,according,Segi,Joinpoint,regression,was,used,measure,estimate,annual,percent,Results,increasing,after,coinciding,introduction,screening,increased,which,mainly,driven,by,men,individuals,aged,above,target,Conclusions,disease,remains,serious,especially,among,benefits,have,been,partially,proven,providing,important,insights,into,better,wider,application,programs,Disease,Regression,analysis,Screening
AB值：
0.498413
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