典型文献
A Triphenylphosphonium Functionalized AIE Conjugated Macro-cyclic Tetramaleimide for Mitochondrial-targeting Bioimaging
文献摘要：
Development of subcellular organelle-targeted bioimaging probes is of great importance in the field of early detection of diseases and exploring the behaviors of subcellular organelles Herein,we present a triphenylphosphonium functionalized conjugated mac-rocyclic tetramaleimide (TPP-CMT) as a mitochondrial-targeting bioimaging probe.The core of TPP-CMT is obtained by connecting two pyrenes and two benzenes through four maleimides This unique structure endows TPP-CMT with exceptional far red/near-infrared aggregation-induced emission (FR/NIR-AIE)characteristics.TPP-CMT is an excellent fluorescent emitter in most solvents and even in solid states.The quantum yield of TPP-CMT was higher than 27％ when dissolved in common middle-polarity organic solvent and this value remained at 28.2％ in its solid state.The introduction of four triphenylphosphonium on maleimide po-sitions endows TPP-CMT with mitochondrial-targeting ability.Thanks to the FR/NIR-AIE characteristics and the mitochondri-al-targeting ability,this well-designed fluorescent probe was successfully employed for mitochondrial targeting bioimaging of HeLa and HepG2 cells.
文献关键词：
中图分类号：
作者姓名：
Wei Zeng;Mao-Hua Lin;Ling-Yun Zhu;Mei-Jin Lin
作者机构：
Key Laboratory of Molecule Synthesis and Function Discovery,College of Chemistry,Fuzhou University,Fuzhou,Fujian 350116,China;College of Materials Science and Engineering,Fuzhou University,Fuzhou,Fujian 350116,China
文献出处：
引用格式：
[1]Wei Zeng;Mao-Hua Lin;Ling-Yun Zhu;Mei-Jin Lin-.A Triphenylphosphonium Functionalized AIE Conjugated Macro-cyclic Tetramaleimide for Mitochondrial-targeting Bioimaging)[J].中国化学（英文版）,2022(01):39-45
A类：
Triphenylphosphonium,Tetramaleimide,rocyclic,tetramaleimide,pyrenes,maleimides,maleimide,mitochondri
B类：
Functionalized,AIE,Conjugated,Macro,Mitochondrial,targeting,Bioimaging,Development,subcellular,targeted,bioimaging,probes,great,importance,field,early,detection,diseases,exploring,behaviors,organelles,Herein,present,triphenylphosphonium,functionalized,conjugated,mac,TPP,CMT,mitochondrial,core,obtained,by,connecting,two,benzenes,through,four,This,unique,structure,endows,exceptional,far,near,infrared,aggregation,induced,emission,FR,NIR,characteristics,excellent,fluorescent,emitter,most,solvents,even,solid,states,quantum,yield,was,higher,than,when,dissolved,common,middle,polarity,organic,this,value,remained,its,introduction,sitions,ability,Thanks,well,designed,successfully,employed,HeLa,HepG2,cells
AB值：
0.526127
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