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典型文献
Carbon quantum dots/Bi4O5Br2 photocatalyst with enhanced photodynamic therapy:killing of lung cancer (A549) cells in vitro
文献摘要:
Inorganic photocatalysts have been regarded as a promising candidate in the domain of tumor photody-namic therapy (PDT) due to their inspirational photocat-alytic activity.In this study,a Bi4O5Br2 photocatalyst was synthesized and it exhibited effective photo-killing activity of A549 cells (a human lung carcinoma epithelial cell line)in vitro.On this basis,we modified Bi4O5Br2 with carbon quantum dots (CQDs) via a hydrolysis method at room temperature,which resulted in an improved photo-killing effect of Bi4O5Br2 to A549 cells.The samples and the interaction between samples and cells were fully charac-terized.It has been found that the loading of CQDs on Bi4O5Br2 can reduce the hydration ratio,increase the cel-lular uptake and improve the photogenerated reactive oxygen species (ROS) as compared with pristine Bi4O5Br2.Electron spin resonance (ESR) analysis and radical-trap-ping experiments manifested that the ROS contributed to PDT may be ·O2-and ·OH.This study may provide a useful strategy to ameliorate the penetrability,cell com-patibility and PDT effect upon cancer cells of other inor-ganic photocatalysts.
文献关键词:
作者姓名:
Bing He;Hai-Yan Jin;Ya-Wen Wang;Cai-Mei Fan;Yun-Fang Wang;Xiao-Chao Zhang;Jian-Xin Liu;Rui Li;Jue-Wen Liu
作者机构:
College of Chemistry and Chemical Engineering,Taiyuan University of Technology,Taiyuan 030024,China;Department of Chemistry,University of Waterloo,Waterloo,ON N2L 3G1,Canada
引用格式:
[1]Bing He;Hai-Yan Jin;Ya-Wen Wang;Cai-Mei Fan;Yun-Fang Wang;Xiao-Chao Zhang;Jian-Xin Liu;Rui Li;Jue-Wen Liu-.Carbon quantum dots/Bi4O5Br2 photocatalyst with enhanced photodynamic therapy:killing of lung cancer (A549) cells in vitro)[J].稀有金属(英文版),2022(01):132-143
A类:
photody
B类:
Carbon,quantum,dots,Bi4O5Br2,enhanced,photodynamic,therapy,killing,lung,cancer,A549,cells,vitro,Inorganic,photocatalysts,have,been,regarded,promising,candidate,domain,tumor,PDT,due,their,inspirational,alytic,activity,this,study,was,synthesized,exhibited,effective,human,carcinoma,epithelial,line,On,basis,modified,carbon,CQDs,via,hydrolysis,method,room,temperature,which,resulted,improved,samples,interaction,between,were,fully,charac,terized,It,has,found,that,loading,reduce,hydration,increase,lular,uptake,photogenerated,reactive,oxygen,species,ROS,compared,pristine,Electron,spin,resonance,ESR,analysis,radical,trap,ping,experiments,manifested,contributed,may,O2,This,provide,useful,strategy,ameliorate,penetrability,patibility,upon,other,inor
AB值:
0.571649
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