典型文献
Characteristics of animal models for COVID-19
文献摘要：
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), the most consequential pandemic of this century, threatening human health and public safety. SARS-CoV-2 has been continuously evolving through mutation of its genome and variants of concern have emerged. The World Health Organization R&D Blueprint plan convened a range of expert groups to develop animal models for COVID-19, a core requirement for the prevention and control of SARS-CoV-2 pandemic. The animal model construction techniques developed during the SARS-CoV and MERS-CoV pandemics were rapidly deployed and applied in the establishment of COVID-19 animal models. To date, a large number of animal models for COVID-19, including mice, hamsters, minks and nonhuman primates, have been established. Infectious diseases produce unique mani-festations according to the characteristics of the pathogen and modes of infection. Here we classified animal model resources around the infection route of SARS-CoV-2, and summarized the characteristics of the animal models constructed via transnasal, localized, and simulated transmission routes of infection.
文献关键词：
中图分类号：
作者姓名：
Feifei Qi;Chuan Qin
作者机构：
Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious Diseases,NHC Key Laboratory of Human Disease Comparative Medicine,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences and Comparative Medicine Center,Peking Union Medical College,Beijing,China;National Center of Technology Innovation for Animal Model,Beijing,China
文献出处：
引用格式：
[1]Feifei Qi;Chuan Qin-.Characteristics of animal models for COVID-19)[J].动物模型与实验医学（英文）,2022(05):401-409
A类：
Blueprint,minks,festations
B类：
Characteristics,animal,models,Severe,acute,respiratory,syndrome,coronavirus,SARS,CoV,causative,agent,most,consequential,this,century,threatening,health,public,safety,has,been,continuously,evolving,through,mutation,its,genome,variants,concern,have,emerged,World,Health,Organization,plan,convened,range,expert,groups,core,requirement,prevention,control,construction,techniques,developed,during,MERS,pandemics,were,rapidly,deployed,applied,establishment,To,date,large,number,including,mice,hamsters,nonhuman,primates,established,Infectious,diseases,produce,unique,mani,according,characteristics,pathogen,modes,infection,Here,classified,resources,around,summarized,constructed,via,transnasal,localized,simulated,transmission,routes
AB值：
0.614224
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
