典型文献
Fibrinolytic therapy for COVID-19:a review of case series
文献摘要：
Thromboembolism is the leading cause of mortality in COVID-19 patients.Thrombi,including pulmonary embolism(PE)and deep vein thrombosis(DVT),range from minor sequelae to fatal complications of SARS-CoV-2 infection[1].Individuals with pre-existing conditions are more likely to develop thrombi and have poor outcomes[2].The guidelines from professional societies for the use of fibrinolytic therapy(FT)in COVID-19 are inconsistent[3].The outcomes of FT for ARDS(acute respiratory distress syndrome)associated with COVID-19 have not been clarified to date.We have summarized 105 COVID-19 patients treated with alteplase(tPA).tPA was applied for thrombolytic(fibrinolytic,generally after the failure of heparin),salvage(rescue for gravely ill patients),or prophylactic therapies for those with a potential of thrombosis[4].We have compared the morbidity,mortality,complications,laboratory tests of COVID-19 patients with ARDS versus those without ARDS(non-ARDS),and adverse events of fibrinolytic therapy.
文献关键词：
中图分类号：
作者姓名：
Hong-Long Ji;Yuling Dai;Runzhen Zhao
作者机构：
Department of Cellular and Molecular Biology,University of Texas at Tyler Health Science Center,Tyler,TX,USA;Texas Lung Injury Institute,University of Texas at Tyler Health Science Center,Tyler,TX,USA;Department of Epidemiology,University of Alabama at Birmingham,Birmingham,AL,USA
文献出处：
引用格式：
[1]Hong-Long Ji;Yuling Dai;Runzhen Zhao-.Fibrinolytic therapy for COVID-19:a review of case series)[J].中国药理学报（英文版）,2022(08):2168-2170
A类：
Fibrinolytic,Thrombi,thrombi
B类：
therapy,review,case,series,Thromboembolism,leading,cause,mortality,patients,including,pulmonary,PE,deep,vein,thrombosis,DVT,range,from,minor,sequelae,fatal,complications,SARS,CoV,infection,Individuals,pre,existing,conditions,more,likely,develop,have,poor,outcomes,guidelines,professional,societies,fibrinolytic,FT,inconsistent,ARDS,acute,respiratory,distress,syndrome,associated,not,been,clarified,date,We,summarized,treated,alteplase,tPA,was,applied,thrombolytic,generally,after,failure,heparin,salvage,rescue,gravely,ill,prophylactic,therapies,those,potential,compared,morbidity,laboratory,tests,versus,without,adverse,events
AB值：
0.607914
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