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典型文献
Animal models in the study of Alzheimer's disease and Parkinson's disease: A historical perspective
文献摘要:
Alzheimer's disease and Parkinson's disease are two of the most prevalent and disa-bling neurodegenerative diseases globally. Both are proteinopathic conditions and while occasionally inherited, are largely sporadic in nature. Although the advances in our understanding of the two have been significant, they are far from complete and neither diagnosis nor the current practices in treatment and rehabilitation is ad-equately helpful. Animal models have historically found application as testing beds for novel therapeutics and continue to be valuable aids in pharmacological research. This review chronicles the development of those models in the context of Alzheimer's and Parkinson's disease, and highlights the shifting paradigms in studying two human- specific conditions in non- human organisms.
文献关键词:
作者姓名:
Rajashree Banerjee;Arushi Rai;Shreyas M.Iyer;Sonia Narwal;Meghana Tare
作者机构:
Department of Biological Sciences,Birla Institute of Technology and Science, Pilani,India
引用格式:
[1]Rajashree Banerjee;Arushi Rai;Shreyas M.Iyer;Sonia Narwal;Meghana Tare-.Animal models in the study of Alzheimer's disease and Parkinson's disease: A historical perspective)[J].动物模型与实验医学(英文),2022(01):27-37
A类:
proteinopathic,equately
B类:
Animal,models,Alzheimer,Parkinson,perspective,are,two,most,prevalent,disa,bling,neurodegenerative,diseases,globally,Both,conditions,while,occasionally,inherited,largely,sporadic,nature,Although,advances,our,understanding,have,been,significant,they,far,from,complete,neither,diagnosis,nor,current,practices,treatment,rehabilitation,helpful,historically,found,application,testing,beds,novel,therapeutics,continue,valuable,aids,pharmacological,research,This,review,chronicles,development,those,context,highlights,shifting,paradigms,studying,human,specific,organisms
AB值:
0.634921
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