典型文献
Impact of Coronary Artery Anatomy in Arterial Switch Operation:In-hospital and Post-discharge Outcomes
文献摘要：
The influence of the coronary artery anatomy on the prognosis of patients receiving an arterial switch operation(ASO)is currently controversial,and the risk factors for this operation may change in more complicated patients.This study aimed to investigate the influence of coronary artery anomalies on the in-hospital and post-discharge outcomes of ASO in patients with transposition of the great arteries(TGA)and Taussig-Bing anomaly(TBA).Methods:We retrospectively reviewed 206 patients who underwent ASO from January 2007 to December 2019.The median age at operation was 33[interquartile range(IQR):20-71]days.Median follow-up time was 7.2 years(IQR:4.0-10.3 years).Results:Coronary anomalies were present in 86 patients(41.7％),with 9(4.4％)of them having a single coronary artery.Additional coronary features included intramural courses in 5(2.4％)patients,ostial stenosis in 1(0.5％)patient,and accessory coronary artery orifices in 5(2.4％)patients.There were 32(15.5％)in-hospital deaths and 8(4.6％)post-discharge deaths,yielding an overall survival of 81.3％,80.7％and 79.9％at 1,5 and 10 years,respectively.Mortality due to ASO has been drastically decreased since 2013.Patients with a single coronary artery had higher rate of in-hospital mortality,but this finding was not statistically significant.The earlier surgical era(OR:2.756)and a longer cardiopulmonary bypass time(OR:2.336)were significantly associated with in-hospital mortality,while coronary patterns were not.An intramural coronary artery(HR:10.034)and a patient age of older than 1 year at the time of ASO(HR:9.706)were independent predictors of post-discharge mortality.Conclusion:ASO remains the procedure of choice for TGA with coronary anomalies with acceptable in-hospital and post-discharge outcomes in terms of overall survival and freedom of reoperation.However,intramural coronary artery is an independent risk factor for post-discharge mortality.Timely surgery within the 1st year of life helps improve overall midterm survival of ASO.
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作者姓名：
Shu-yuan WANG;Qing-yu ZENG;Li ZHANG;Qing LV;Ming-xing XIE
作者机构：
Department of Ultrasound,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China;Clinical Research Center for Medical Imaging in Hubei Province,Wuhan 430022,China;Hubei Province Key Laboratory of Molecular Imaging,Wuhan 430022,China;Shenzhen Huazhong University of Science and Technology Insititute,Shenzhen 518057,China
文献出处：
引用格式：
[1]Shu-yuan WANG;Qing-yu ZENG;Li ZHANG;Qing LV;Ming-xing XIE-.Impact of Coronary Artery Anatomy in Arterial Switch Operation:In-hospital and Post-discharge Outcomes)[J].当代医学科学(英文),2022(03):642-649
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0.545505
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