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Estimation of Iron Physiological Requirement in Chinese Children using Single Stable Isotope Tracer Technique
文献摘要:
Objective This study is to obtain precise data on iron physiological requirements in Chinese children using single stable isotope tracer technique.Methods Thirty boys (10.6 ± 0.2 years) and 27 girls (10.4 ± 0.2 years) were received oral 6 mg 57Fe each day for 5 consecutive days. Venous blood samples were subsequently drawn to examine the change of total iron concentration and 57Fe abundance at day 0, 14, 28, 60, 90, 180, 360, 450, 540, 630, 720. The iron physiological requirement was calculated by iron loss combined with iron circulation rate once 57Fe abundance stabilized in human body. Results The iron physiological requirement was significantly lower in boys than those values in girls (16.88 ± 7.12 vs. 18.40 ± 8.81 μg/kg per day, P < 0.05). Correspondingly, the values were calculated as 722.46 ± 8.43 μg/day for boys and 708.40 ± 7.55 μg/day for girls, respectively. Considering nearly 10%iron absorption rate, the estimated average iron physiological requirement was 6.0 mg/day in boys and 6.2 mg/day in girls. Conclusion This study indicate that iron physiological requirement could require more daily iron intake in girls as compare with the values in boys having the same body weight. These findings would be facilitate to the new revised dietary reference intakes.
文献关键词:
作者姓名:
ZHANG Yu;LIU Xiao Bing;REN Tong Xiang;CAI Jie;LU Jia Xi;NIU Ran;PIAO Jian Hua;YANG Li Chen;WANG Jun;YANG Xiao Guang
作者机构:
Chinese Center for Disease Control and Prevention,Beijing 102206,China;Gansu Center for Disease Control and Prevention,Gansu 73000,Lanzhou,China;Key Laboratory of Trace Element Nutrition,MOH,National Institute for Nutrition and Health,Chinese Center for Disease Control and Prevention,Beijing 100050,China;National Institute of Metrology,Beijing 100029,China;Department of General Surgery,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China
引用格式:
[1]ZHANG Yu;LIU Xiao Bing;REN Tong Xiang;CAI Jie;LU Jia Xi;NIU Ran;PIAO Jian Hua;YANG Li Chen;WANG Jun;YANG Xiao Guang-.Estimation of Iron Physiological Requirement in Chinese Children using Single Stable Isotope Tracer Technique)[J].生物医学与环境科学(英文版),2022(08):681-687
A类:
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AB值:
0.552975
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