典型文献
Cost-effectiveness analysis on COVID-19 surveillance strategy of large-scale sports competition
文献摘要：
Background::Nucleic acid test (NAT) could effectively control the spread of COVID-19 caused by large-scale sports competitions. However, quantitative analysis on the appropriate frequency of NAT is scarce, and the cost-effectiveness and necessity of high-frequency NAT remain to be fully explored and validated. This study aims to optimize the COVID-19 surveillance strategies through cost-effectiveness analysis for the Tokyo 2020 Olympic Games and the upcoming Beijing 2022 Olympic Winter Games.Methods::A total of 18 scenarios were designed regarding the NAT frequency, symptom monitoring, and strengthening close-contact control. An agent-based stochastic dynamic model was used to compare the cost-effectiveness of different NAT scenarios and optimize the surveillance strategies. The dynamics of the proposed model included the arrival and departure of agents, transmission of the disease according to Poisson processes, and quarantine of agents based on regular NATs and symptom onset. Accumulative infections, cost, and incremental cost-effectiveness ratio (ICER) were simulated in the frame of the model. ICER was used to compare the cost-effectiveness of different scenarios. Univariate sensitivity analysis was performed to test the robustness of the results.Results::In Scenario 16, where the competition-related personnel (CRP) received NAT daily and national sports delegation (NSD) with quarantined infections accepted an additional NAT daily, accumulative infection was 320.90 (90 initial infections), the total cost was (United States Dollar) USD 8 920 000, and the cost of detecting out each infection was USD 27 800. Scenario 16 would reduce the total cost by USD 22 570 000 (avoid 569.61 infections), USD 1 420 000 (avoid 47.2 infections) compared with Scenario 10 (weekly NAT, strengthened close contact control) and Scenario 7 (daily NAT, no strengthened close contact control), respectively. Sensitivity analysis showed that the result was most sensitive to the change in basic reproductive number.Conclusions::High-frequency NATs such as bidaily, daily, and twice a day were cost-effective. NAT daily for CRP with strengthening close-contact control could be prioritized in defense against COVID-19 at large-scale sports competitions. This study could assist policymakers by assessing the cost-effectiveness of NAT scenarios and provide the host country with an optimal COVID-19 surveillance strategy.
文献关键词：
Cost-effectiveness;Sports competition;Surveillance;COVID-19;Nucleic acid test;Stochastic dynamic model
中图分类号：
作者姓名：
Wang Xuechun;Cai Yiru;Zhang Bo;Zhang Xiangyu;Wang Lianhao;Yan Xiangyu;Zhao Mingchen;Zhang Yuan;Jia Zhongwei
作者机构：
School of Public Health, Peking University, Beijing 100191, China;School of Mathematical Sciences, Peking University, Beijing 100871, China;Center for Statistical Sciences, Peking University, Beijing, China;Center for Intelligent Public Health, Institute for Artificial Intelligence, Peking University, Beijing, China;Peking University Clinical Research Institute, Peking University, Beijing, China
文献出处：
引用格式：
[1]Wang Xuechun;Cai Yiru;Zhang Bo;Zhang Xiangyu;Wang Lianhao;Yan Xiangyu;Zhao Mingchen;Zhang Yuan;Jia Zhongwei-.Cost-effectiveness analysis on COVID-19 surveillance strategy of large-scale sports competition)[J].贫困所致传染病（英文）,2022(02):53-62
A类：
NATs,bidaily
B类：
Cost,effectiveness,analysis,surveillance,strategy,large,scale,sports,Background,Nucleic,acid,test,could,effectively,control,spread,caused,by,competitions,However,quantitative,appropriate,frequency,scarce,cost,necessity,high,remain,fully,explored,validated,This,study,aims,optimize,strategies,through,Tokyo,Olympic,Games,upcoming,Beijing,Winter,Methods,total,scenarios,were,designed,regarding,symptom,monitoring,strengthening,close,contact,An,stochastic,model,was,different,dynamics,proposed,included,arrival,departure,agents,transmission,disease,according,Poisson,processes,regular,onset,Accumulative,infections,incremental,ratio,ICER,simulated,frame,Univariate,sensitivity,performed,robustness,results,Results,In,Scenario,where,related,personnel,received,national,delegation,NSD,quarantined,accepted,additional,accumulative,initial,United,States,Dollar,USD,detecting,out,each,would,reduce,avoid,compared,weekly,strengthened,no,respectively,Sensitivity,showed,that,most,sensitive,change,basic,reproductive,number,Conclusions,High,such,twice,day,prioritized,defense,against,assist,policymakers,assessing,provide,host,country,optimal,Sports,Surveillance,Stochastic
AB值：
0.459762
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
