典型文献
Application of Nanopore Sequencing Technology in the Clinical Diagnosis of Infectious Diseases
文献摘要：
Infectious diseases are an enormous public health burden and a growing threat to human health worldwide. Emerging or classic recurrent pathogens, or pathogens with resistant traits, challenge our ability to diagnose and control infectious diseases. Nanopore sequencing technology has the potential to enhance our ability to diagnose, interrogate, and track infectious diseases due to the unrestricted read length and system portability. This review focuses on the application of nanopore sequencing technology in the clinical diagnosis of infectious diseases and includes the following: (i) a brief introduction to nanopore sequencing technology and Oxford Nanopore Technologies (ONT) sequencing platforms;(ii) strategies for nanopore-based sequencing technologies; and (iii) applications of nanopore sequencing technology in monitoring emerging pathogenic microorganisms, molecular detection of clinically relevant drug-resistance genes, and characterization of disease-related microbial communities. Finally, we discuss the current challenges, potential opportunities, and future outlook for applying nanopore sequencing technology in the diagnosis of infectious diseases.
文献关键词：
中图分类号：
作者姓名：
ZHANG Lu Lu;ZHANG Chi;PENG Jun Ping
作者机构：
NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100176, China;Key Laboratory of Respiratory Disease Pathogenomics,Chinese Academy of Medical Sciences, Beijing 100176, China
文献出处：
引用格式：
[1]ZHANG Lu Lu;ZHANG Chi;PENG Jun Ping-.Application of Nanopore Sequencing Technology in the Clinical Diagnosis of Infectious Diseases)[J].生物医学与环境科学（英文版）,2022(05):381-392
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AB值：
0.589196
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