典型文献
2022 Chinese national clinical practice guideline on
Helicobacter pylori eradication treatment
文献摘要：
Background::Helicobacter pylori (
H. pylori) infection is an infectious disease with a prevalence rate of up to 50% worldwide. It can cause indigestion, gastritis, peptic ulcer, and gastric cancer.
H. pylori eradication treatment can effectively control disease progression and reduce the risk of the above conditions. However, the escalating trend of antibiotic resistance presents a global challenge for
H. pylori eradication. We aim to provide guidance on pharmacological treatment of
H. pylori infection.
Methods::This clinical practice guideline is developed following the World Health Organization’s recommended process, adopting Grading of Recommendations Assessment, Development and Evaluation in assessing evidence quality, and utilizing Evidence to Decision framework to formulate clinical recommendations, minimizing bias and increasing transparency of the clinical practice guideline development process. We used the Reporting Items for practice Guidelines in HealThcare (RIGHT) statement and The Appraisal of Guidelines for Research and Evaluation II (AGREE II) as reporting and conduct guides to ensure the guideline’s completeness and transparency.Results::Though decreasing in developed countries, the prevalence of
H. pylori remains high in developing countries, causing a major public health burden. This clinical practice guideline contains 12 recommendations concerning pharmacological treatment for
H. pylori eradication. Among them, it is worth highlighting that bismuth preparations are inexpensive, safe, and effective, consequently making bismuth quadruple therapy a preferred choice for initial and rescue treatment. In empirical treatment, high-dose dual therapy is equally effective compared with bismuth quadruple therapy.
Conclusions::The 12 recommendations in this clinical practice guideline are formed with consideration for stakeholders’ values and preferences, resource use, feasibility, and acceptability. Recommendations are generalizable to resource limited settings with similar antibiotic resistance pattern as China, and lower middle-income countries facing comparable sociological and technical challenges.Registration::Guidelines International Network (GIN) website, .
文献关键词：
Helicobacter pylori;Peptic ulcer;Guideline;Pharmacological treatment
中图分类号：
作者姓名：
Zhou Liya;Lu Hong;Song Zhiqiang;Lyu Bin;Chen Ye;Wang Jiyao;Xia Jun;Zhao Zhan
作者机构：
Department of Gastroenterology, Peking University Third Hospital, Beijing 100191, China;Department of Gastroenterology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China;Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310018, China;Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China;Department of Gastroenterology, Fudan University Affiliated Zhongshan Hospital, Shanghai 200032, China;Nottingham Ningbo GRADE Center, Nottingham China Health Institute, University of Nottingham Ningbo China, Ningbo, Zhejiang 315100, China;Academic Unit of Lifespan and Population Health, School of Medicine, The University of Nottingham, Nottingham, UK;Systematic Review Solutions Ltd, Shanghai 201403, China
文献出处：
引用格式：
[1]Zhou Liya;Lu Hong;Song Zhiqiang;Lyu Bin;Chen Ye;Wang Jiyao;Xia Jun;Zhao Zhan-.2022 Chinese national clinical practice guideline on
Helicobacter pylori eradication treatment
)[J].中华医学杂志（英文版）,2022(24):2899-2910
A类：
treatment
,indigestion,HealThcare
B类：
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AB值：
0.582828
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