典型文献
Retinal microglial activation in glaucoma: evolution over time in a unilateral ocular hypertension model
文献摘要：
Glaucoma is a neurodegenerative chronic pathology, characterized by the loss of retinal ganglion cells (RGC), which leads to an irreversible vision field loss. The increased intraocular pressure (IOP) constitutes its main risk factor. Nowadays, the main treatments for glaucoma are focused on decreasing IOP; nevertheless, the progression of the disease continues, despite IOP control. This fact shows the existence of other factors that could contribute to the advance of glaucomatous neurodegeneration. The early diagnostics, the use of neuroprotective therapies, and knowledge of the pathological processes are the major challenges associated with the management of this disease. Different pathogenic mechanisms have been proposed to be responsible for RGC death, including oxidative stress, mitochondrial dysfunction, glutamate excitotoxicity, and neuroinflammation (Casson et al., 2012).
文献关键词：
中图分类号：
作者姓名：
José A.Fernández-Albarral
作者机构：
Instituto de Investigaciones Oftalmológicas Ramón Castroviejo,Universidad Complutense de Madrid,Madrid,Spain;Facultad de óptica y Optometría,Departamento de Inmunología,Oftalmología y ORL,Universidad Complutense de Madrid,Madrid,Spain
文献出处：
引用格式：
[1]José A.Fernández-Albarral-.Retinal microglial activation in glaucoma: evolution over time in a unilateral ocular hypertension model)[J].中国神经再生研究（英文版）,2022(04):797-799
A类：
glaucomatous
B类：
Retinal,microglial,activation,evolution,over,unilateral,hypertension,model,Glaucoma,neurodegenerative,chronic,pathology,characterized,by,loss,retinal,ganglion,cells,RGC,which,leads,irreversible,vision,field,increased,intraocular,pressure,IOP,constitutes,its,main,risk,Nowadays,treatments,are,focused,decreasing,nevertheless,progression,disease,continues,despite,control,This,shows,existence,other,factors,that,could,contribute,advance,neurodegeneration,early,diagnostics,neuroprotective,therapies,knowledge,pathological,processes,major,challenges,associated,management,this,Different,pathogenic,mechanisms,have,been,proposed,responsible,death,including,oxidative,stress,mitochondrial,dysfunction,glutamate,excitotoxicity,neuroinflammation,Casson
AB值：
0.715986
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
