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典型文献
Self-powered anti-interference photoelectrochemical immunosensor based on Au/ZIS/CIS heterojunction photocathode with zwitterionic peptide anchoring
文献摘要:
Accurate detection of important biomarkers with ultra-low levels in complex biological matrix is one of the frontier scientific issues because of possible signal interference of potential reductive agents and pro-tein molecules.Herein,a self-powered anti-interference photoelectrochemical(PEC)immunosensor was explored for sensitive and specific detection of model target of cardiac troponin I(cTnI).Specifically,a novel ternary heterojunction served as the photocathode to offer a remarkable current output and a zwit-terionic peptide was introduced to build a robust antifouling biointerface.CulnS2(CIS)film with porous network nanostructure was first prepared and then modified in order with ZnIn2S4(ZIS)nanocrystals and Au nanoparticles to fabricate the Au/ZIS/CIS heterojunction photocathode.After capture cTnl anti-body(Ab)was immobilized,the zwitterionic peptide KAEAKAEAPPPPC was then anchored to compete the immunosensor.The elaborated PEC immunosensor exhibited high sensitivity for target cTnI antigen(Ag)detection,with good anti-interference against reductive agents and nonspecific proteins.This integration strategy of heterojunction photocathode with zwitterionic peptide provides a new sight to develop ad-vanced PEC immunosensors applying in practical biosamples.
文献关键词:
作者姓名:
Ze Hu;Yaqun Xu;Hao Wang;Gao-Chao Fan;Xiliang Luo
作者机构:
Shandong Key Laboratory of Biochemical Analysis,College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao 266042,China;State Key Laboratory of Chemo/Biosensing and Chemometrics,College of Chemistry and Chemical Engineering,Hunan University,Changsha 410082,China
引用格式:
[1]Ze Hu;Yaqun Xu;Hao Wang;Gao-Chao Fan;Xiliang Luo-.Self-powered anti-interference photoelectrochemical immunosensor based on Au/ZIS/CIS heterojunction photocathode with zwitterionic peptide anchoring)[J].中国化学快报(英文版),2022(11):4750-4755
A类:
zwit,terionic,CulnS2,KAEAKAEAPPPPC,biosamples
B类:
Self,powered,interference,photoelectrochemical,Au,ZIS,CIS,heterojunction,photocathode,zwitterionic,peptide,anchoring,Accurate,detection,important,biomarkers,ultra,low,levels,complex,biological,matrix,one,frontier,scientific,issues,because,possible,signal,potential,reductive,agents,molecules,Herein,self,PEC,was,explored,sensitive,model,target,cardiac,troponin,cTnI,Specifically,novel,ternary,served,offer,remarkable,current,output,introduced,build,robust,antifouling,biointerface,film,porous,network,nanostructure,first,prepared,then,modified,order,ZnIn2S4,nanocrystals,nanoparticles,fabricate,After,capture,cTnl,body,Ab,immobilized,anchored,compete,elaborated,exhibited,high,sensitivity,antigen,Ag,good,against,nonspecific,proteins,This,integration,strategy,provides,new,sight,develop,ad,vanced,immunosensors,applying,practical
AB值:
0.56114
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